Side effects glyburide glipizide
metformin NC
MOA Pioglitazone Rosiglitazone
Side effects metformin
classification thiazolidinediones
MOA metformin
Side effects of Pioglitazone Rosiglitazone
sulfuonylureas classification
classification biguanide
glyburide glipizide MOA
decrease absorption of glucose decrease glucose production increase insulin sensitivity by increase uptake in tissue
hypoglycemia weight gain contraindicated with sulfa allergy
EDEMA liver failure CHF weight gain
risk of lactic acidosis
Pioglitazone Rosiglitazone
GI side effects, N/V/D weight lose contraindicated if impaired liver/renal function little risk for hypoglycemia
metformin
Glyburide Glipizide
act in beta cells in the pancreas to stimulate increase in insulin production and increase number of insulin receptors
decreases insulin resistance decreases glucose output in the liver
