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Step 2 of Bone Remodeling

Osteoblast

Calcitonin

Step 1 of Bone Remodeling

Hypocalcemia

Osteoclast

Thyroid gland

Parathyroid hormone

Step 4 of Bone Remodeling

Hypercalcemia

Step 3 of Bone Remodeling

Parathyroid

Bone Remodeling - Compact bone replaces woven bone. Internal callus removed. Medullary cavity is restored

Releases parathyroid hormone

Builds bone

Bony Callus Formation. Takes several weeks to months. Osteoclasts break down fibrous cartilage Osteoblasts lay new bone matrix, made of osteocytes. Bone is MOSTLY healed at this stage

A hematoma is a “blood tumor” that forms at the site of the break This painful, swollen area fills with blood from the broken blood vessels

High calcium levels

Low calcium levels

Breaks down bone

Fibrocartilaginous callus formation. Connective tissue stem cells & capillary blood vessels penetrate. Phagocytes clear away junk. Cartilage and blood vessels start to form to create new bone

Releases calcitonin

A hormone that lowers Ca in blood by stimulating bone to be built.

A hormone that increases Ca in the blood by stimulating bone to be broken down.