Antidepressant Med Data Online version Match the need to know data with the correct antidepressant drug class. by Lisa Schilling-Kauten 1 SSRI Drugs 2 MAOI Drugs 3 TCA Drugs 4 Atypical Drugs 5 SNRI Drugs Common s/e weight gain, insomnia, nausea, sexual dysfunction Fewest side effects of all antidepressants Good for use in adults with SI, least risk of suicide by OD Increased SI noted in children/adolescents Avoid anticoagulants, other serotonin agonists, (triptans), opiate derivatives, & lithium Monitor BP & heart rate for orthostatic changes Must follow a tyramine-free diet Contraindications: SSRIs, TCAs, buspirone (BuSpar), opiate derivatives, dextromethorphan Use cautiously w/diabetes, seizure disorders, or w/antihypertensive use Contraindications: pheochromocytoma, heart, vascular or kidney dysfunction Has the only medication that can be used transdermal Takes 4-8 weeks to take full effect Cause anticholinergic S/E Can increase suicide risk r/t high risk for lethality w/toxic dose Avoid dehydration, increases hypotension risk Contraindication: client’s who have seizure disorders Zyban brand of bupropion: used for smoking cessation, reduces cravings Trazadone is often used for a sleep aid Bupropion contraindications: seizure disorder, MAOI use, anorexia or bulimia Each drug has it is own mechanism of action & indications Not an SSRI, but high risk of serotonin syndrome Monitor for weight loss & increases in B/P Monitor for hyponatremia (especially elderly) Duloxetine (Cymbalta) can exacerbate liver issues
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