Contraindications: pheochromocytoma, heart, vascular or kidney dysfunction
Avoid anticoagulants, other serotonin agonists, (triptans), opiate derivatives, & lithium
Trazadone is often used for a sleep aid
Contraindication: client’s who have seizure disorders
Common s/e weight gain, insomnia, nausea, sexual dysfunction
Monitor for weight loss & increases in B/P
Takes 4-8 weeks to take full effect
Bupropion contraindications: seizure disorder, MAOI use, anorexia or bulimia
Zyban brand of bupropion: used for smoking cessation, reduces cravings
Cause anticholinergic S/E
Not an SSRI, but high risk of serotonin syndrome
Monitor for hyponatremia (especially elderly)
Use cautiously w/diabetes, seizure disorders, or w/antihypertensive use
Increased SI noted in children/adolescents
Can increase suicide risk r/t high risk for lethality w/toxic dose
Contraindications: SSRIs, TCAs, buspirone (BuSpar), opiate derivatives, dextromethorphan
Fewest side effects of all antidepressants
Avoid dehydration, increases hypotension risk
Each drug has it is own mechanism of action & indications
Has the only medication that can be used transdermal
Good for use in adults with SI, least risk of suicide by OD
Must follow a tyramine-free diet
Monitor BP & heart rate for orthostatic changes
Duloxetine (Cymbalta) can exacerbate liver issues
