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1. 
F-18 is used for what types of scans dealing with the brain?
A.
Tumor imaging
B.
Alzheimer's Disease
C.
Epilepsy
D.
Parkinson's Disease
E.
Dacryoscintigraphy
2. 
FDG crosses the Blood Brain Barrier?
A.
True
B.
False
3. 
What is the MOL of F-18 FDG?
A.
Compartmental; blood flow lipophilic agent that penetrates BBB.
B.
Based on regional blood flow, distribution based on glucose metabolism.
C.
Based on cerebral blood flow, distribution based on glucose metabolism.
D.
Active Transport; distribution is based on amount of neurotransmitters able to bind to glucose receptors.
4. 
Which PET Brain imaging agent has a dose of 10-20mCi?
A.
F-18 FDG
B.
F-18 Flutemetamol
C.
F-18 Florbetaben
D.
DTPA
5. 
During a PET brain study, the patient should follow what instructions during scan?
A.
Talk or sing to allow certain portions of the brain to accumulate more of the radiotracer.
B.
Refrain from talking and reading, room lights low to reduce sensory stimulus and brain activation.
C.
Maintain silence but allow for internal dialogue of solving math problems or replaying memories.
D.
Pt should answer a series of questions provided by the technologist at intervals during the study.
6. 
Two scans are acquired for attenuation correction, they are?
A.
Emission
B.
Remission
C.
Transmission
D.
Immersion
7. 
A brain tumor that is low grade astrocytoma's is referred to as ?
A.
More aggressive
B.
Moderatly aggressive
C.
Passive
D.
Less aggressive
8. 
A brain tumor that is a High grade glioblastoma multiforme is referred to as?
A.
Less aggressive
B.
More aggressive
C.
Moderately aggressive
D.
Passive
9. 
High grade glioblastoma multiforme make up what percent of brain tumors?
A.
2-5%
B.
6-12%
C.
15-20%
D.
30-45%
10. 
Treatment for brain tumors include surgical resection, external radiotherapy, and chemotherapy.
A.
True
B.
False
11. 
NM scans can help rule out recurrent disease vs. radiation necrosis or lymphoma vs infections
A.
True
B.
False
12. 
What radiopharmaceuticals are used in SPECT brain tumor imaging?
A.
Tc99m-Sulfur Colloid
B.
Tc99m-Sestamibi
C.
Ge-68
D.
TL-201
13. 
HMPAO or ECD are sensitive for brain tumor work?
A.
True
B.
False
14. 
Accumulation of SPECT tracers is less specific than accumulation of PET FDG.
A.
True
B.
False
15. 
Accumulation of SPECT tracers is less specific than accumulation of PET FDG. Why?
A.
Tc99m Sestamibi can accumulate in seizure patients due to BBB breakdown.
B.
TL-201 can accumulate in seizure patients due to BBB breakdown.
C.
TL-201 can accumulate in stroke due to BBB breakdown.
D.
F-18 FDG can accumulate in stroke patients due to BBB breakdown
16. 
Interpretation of PET FDG brain is difficult because of elevated?
A.
Cerebral cortex uptake
B.
Frontal and Parietal lobe uptake
C.
Cerebellum uptake
D.
Medulla oblongata uptake
17. 
Brain tumors need less uptake vs surrounding normal uptake to be visualized.
A.
True
B.
False
18. 
30% of epilepsy patients have no control over there disease.
A.
True
B.
False
19. 
With medications, the surgeon will need what type of imaging in order to see ROI in the brain?
A.
CT
B.
MRI
C.
Dual Head Gamma camera, LEHR collimator
D.
PET
20. 
Which PET radiopharmaceutical can show independent confirmation of the site of epilepsy in the brain?
A.
Florbetapir
B.
Fludeoxyglucose
C.
Flutemetamol
D.
Florbetaben
21. 
Define Ictal state?
A.
Between seizure; both metabolism and blood flow are increased at the site of the onset, shows hot.
B.
During seizure; brain metabolism and blood flow are increased, shows hot.
C.
Between seizure; both metabolism and blood flow are reduced at the site of the onset, shows cold.
D.
During seizure; brain metabolism and blood flow are decreased, shows cold.
22. 
Define Interictal?
A.
Between seizure; both metabolism and blood flow are increased at the site of the onset, shows hot.
B.
During seizure; brain metabolism and blood flow are increased, shows hot.
C.
Between seizure; both metabolism and blood flow are reduced at the site of the onset, shows cold.
D.
During seizure; brain metabolism and blood flow are decreased, shows cold.
23. 
______ epilepsy whare consciousness is impaired?
A.
Frontal lobe
B.
Parietal lobe
C.
Temporal lobe
D.
Occipital lobe
24. 
Which state of epilepsy is more useful when scans are performed for parietal complex?
A.
Interictal
B.
Ictal
C.
Postictal
D.
Preictal
25. 
Most (70%) of patients has ________ on interictal PET FDG scans in the involved regions.
A.
Hypermetabolism
B.
Hypometabolism
C.
Hypoperfusion
D.
Hyperperfusion
26. 
SPECT is useful for regional blood flow _______?
A.
Delayed static post seizure
B.
Planar post seizure
C.
Lateral post seizure
D.
Immediate post seizure
27. 
What non radioactive drug may be used in the assessment of brain perfusion imaging?
A.
Diprydamole
B.
Adenosine
C.
Acetazolamide
D.
Furosemide
28. 
When a normal patient is given acetazolamide, how much does cerebral blood flow increase?
A.
1-2x
B.
2-3x
C.
3-4x
D.
4-5x
29. 
A patient diagnosed with stenosis, autoregulatory vasodilation is in effect, what will happen if acetazolamide is given?
A.
Regional perfusion defect
B.
Hypoglycemia
C.
Cerebral infarction
D.
Localized perfusion defect
30. 
Why does Diamox cause more issues in patients with abnormal conditions within the brain?
A.
Normal vessels cannot dilate to the same extent as abnormal vessels.
B.
Abnormal vessels cannot dilate to the same extent as normal vessels.
C.
Abnormal vessels dilate further then normal vessels risking damage.
D.
Abnormal vessels cannot constrict to the same extent as normal vessels.