Benzene
Can progress to Myelodysplasia then to Leukemia
Antibiotics (chloramphenicol)
Chemotherapy agents
WBC <500
Arsenic
Ionizing radiation
Pancytopenia
Hypocellular marrow
50% Fatality rate b4 BM transplant
Pesticides- organochlorine, lindane
Reticulocytes < 1%
