Interstitial Nephritis
Similiar to ETOH effect on the brain
Proximal Renal Tubular Acidosis (RTA)
Smokig
Headache
Beta-naphthalene
N-acetylatio reduces carcinogenicity (slow increase Blad Ca vs rapid acetylators)
Increased Low Molecular Weight Proteinuria
Asbestos
Paresthesias
Proximal Tubule dysfunction
Benzidine- Confirmed HUMAN CARCINOGEN
Obesity
aniline dyes-1885
4-aminobiphenyl
HTN
Fanconi's Syndrome (80% chronically exposed develop low mw proteinuria)
Trichloroethylene (TCE) IARC 2A
Incoordination
Confusion
Dizziness
Hangover withdrawal sxs on weekends
Renal tract stones (Renal Calcium wasting)
NV
