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The ability to identify founder mutations has profound implications for the practice of medicine . Knowledge of such mutations can , for instance , help physicians identify patients who should be tested for certain diseases . Currently physicians may rely on testing individual ? s ethnicity to assign some diseases risks and perform further tests .

For example , most sickle ____________________ disease occurs in those of African ____________________ . But as the world ? s peoples become more genetically ____________________ , it will become increasingly difficult to ____________________ an ancestral geographic origin or specific ____________________ to any person .

With ethnic background disappearing as a ____________________ clue , physicians will therefore rely on testing individuals ? DNA more as they try to ____________________ disease risks or the cause of patients ? symptoms . And finding founder ____________________ now , while human populations remain genetically ____________________ , will help identify the specific genes responsible for numerous ____________________ .