A
pheochromocytoma
is
a
rare
,
catecholamine
-
secreting
tumor
____________________
from
chromaffin
cells
.
The
term
pheochromocytoma
(
in
Greek
,
phios
means
dusky
,
chroma
means
color
,
and
cytoma
means
tumor
)
refers
to
the
____________________
the
tumor
cells
acquire
when
stained
with
chromium
____________________
.
About
30%
of
pheochromocytomas
occur
as
part
of
____________________
syndromes
.
Although
pheochromocytoma
has
classically
been
associated
with
3
____________________
?
von
Hippel
-
Lindau
(
VHL
)
syndrome
,
multiple
endocrine
neoplasia
type
2
(
MEN
2
)
,
and
____________________
type
1
(
NF1
)
?
there
are
now
10
genes
that
have
been
____________________
as
sites
of
mutations
leading
to
pheochromocytoma
.
These
different
genes
produce
tumors
with
different
ages
of
onset
,
____________________
profiles
,
locations
,
and
potential
for
malignancy
.
Because
of
____________________
catecholamine
secretion
,
pheochromocytomas
may
precipitate
life
-
threatening
hypertension
or
____________________
arrhythmias
.
If
the
diagnosis
of
a
pheochromocytoma
is
____________________
,
the
consequences
can
be
disastrous
,
even
fatal
;
however
,
____________________
a
pheochromocytoma
is
found
,
it
is
potentially
____________________
.
(
See
Pathophysiology
,
Prognosis
,
and
Treatment
.
)
About
85%
of
pheochromocytomas
are
located
within
the
adrenal
____________________
,
and
98%
are
within
the
abdomen
.
When
such
tumors
arise
____________________
of
the
adrenal
gland
,
they
are
termed
extra
-
adrenal
____________________
,
or
paragangliomas
.
Extra
-
adrenal
pheochromocytomas
develop
in
the
____________________
chromaffin
tissue
of
the
nervous
system
.
They
may
occur
____________________
from
the
base
of
the
brain
to
the
____________________
bladder
.
