Graves
disease
,
named
after
Robert
J
.
Graves
,
MD
,
[
1
]
circa
1830s
,
is
an
____________________
disease
characterized
____________________
hyperthyroidism
due
to
circulating
autoantibodies
.
Thyroid
-
stimulating
immunoglobulins
(
TSIs
)
bind
to
and
activate
____________________
receptors
,
causing
the
thyroid
gland
to
grow
and
the
thyroid
follicles
to
increase
synthesis
of
thyroid
hormone
.
Graves
disease
,
along
with
____________________
thyroiditis
,
is
classified
as
an
autoimmune
thyroid
disorder
.
In
some
patients
,
Graves
disease
represents
a
part
of
more
____________________
autoimmune
processes
leading
to
dysfunction
of
multiple
organs
(
eg
,
polyglandular
autoimmune
syndromes
)
.
Graves
disease
is
associated
with
pernicious
____________________
,
vitiligo
,
diabetes
mellitus
type
1
,
autoimmune
adrenal
insufficiency
,
systemic
____________________
,
myasthenia
gravis
,
Sjögren
syndrome
,
rheumatoid
arthritis
,
and
systemic
____________________
erythematosus
.
