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Familial cases have been ____________________ . Mutations in pluripotential cells during embryogenesis may
generate varying lines of differentiation ____________________ in organoid nevi . Nevus sebaceus ____________________ to
respond ____________________ hormonal influences , as the lesion can be ____________________ at birth , become flattened in childhood ,
and become raised again during puberty .
Deletions of the patched gene have been ____________________ in nevus sebaceus and may be ____________________ for the
predisposition to the development ____________________ basal cell carcinoma ____________________ other tumors in this lesion .