In
1962
,
Headington
and
French
first
described
trichilemmoma
as
a
____________________
neoplasm
with
differentiation
toward
pilosebaceous
follicular
epithelium
,
or
____________________
root
sheath
.
Though
benign
in
nature
,
the
significance
of
____________________
resides
in
the
association
with
Cowden
disease
(
ie
,
multiple
hamartoma
syndrome
)
and
the
____________________
to
differentiate
trichilemmomas
from
other
more
aggressive
cutaneous
tumors
,
____________________
as
trichilemmal
carcinoma
.
Clinically
,
trichilemmomas
present
as
well
-
defined
,
____________________
,
asymptomatic
papules
or
verrucoid
growths
.
They
may
appear
as
____________________
solitary
or
multiple
lesions
,
and
are
usually
found
____________________
the
head
and
face
(
see
the
image
below
)
.
These
papules
often
mimic
a
____________________
cell
carcinoma
or
a
verruca
.