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Play Fill in the Blanks Game
In 1962 , Headington and French first described trichilemmoma as a ____________________ neoplasm with
differentiation toward pilosebaceous follicular epithelium , or ____________________ root sheath . Though benign in
nature , the significance of ____________________ resides in the association with Cowden disease ( ie , multiple
hamartoma syndrome ) and the ____________________ to differentiate trichilemmomas from other more aggressive
cutaneous tumors , ____________________ as trichilemmal carcinoma .
Clinically , trichilemmomas present as well - defined , ____________________ , asymptomatic papules or verrucoid
growths . They may appear as ____________________ solitary or multiple lesions , and are usually found ____________________ the head and
face ( see the image below ) . These papules often mimic a ____________________ cell carcinoma or a verruca .