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Rhinoscleroma is a chronic granulomatous condition of the nose ____________________ other structures of the upper
respiratory tract . Rhinoscleroma ____________________ a result of infection by the bacterium Klebsiella rhinoscleromatis .
The Polish surgeon Johann von Mikulich in Wroclaw ____________________ the histologic features in 1877 ; von
Frisch ____________________ the organism in 1882 . In 1932 , Belinov proposed the ____________________ of the term scleroma
respiratorium because the pathologic ____________________ in rhinosclerosis may involve not only the upper airways
but also the lower airways . In 1961 , Steffen and Smith demonstrated that K rhinoscleromatis
conformed to Koch's postulates and that it ____________________ an etiologic factor in the inflammatory changes typical
of ____________________ . The occurrence of familial disease suggests that genetic ____________________ of the host response to
K rhinoscleromatis may be an important factor ____________________ endemic areas . Rhinoscleroma is a chronic
infectious disease of ____________________ countries .