Pemphigus
is
an
autoimmune
bullous
disease
characterized
by
____________________
and
erosions
of
the
skin
and
mucous
membranes
.
Several
____________________
of
the
disease
exist
,
including
pemphigus
vulgaris
,
pemphigus
foliaceous
,
____________________
drug
-
induced
pemphigus
.
Patients
with
drug
-
induced
pemphigus
have
autoantibodies
that
____________________
either
circulating
or
tissue
bound
.
Since
the
1950s
,
evidence
has
____________________
that
drugs
may
cause
or
exacerbate
pemphigus
.
A
____________________
____________________
should
be
considered
in
every
new
patient
with
pemphigus
.
The
most
common
variant
of
____________________
associated
with
drug
exposure
is
pemphigus
foliaceus
,
although
pemphigus
vulgaris
has
also
____________________
described
.
In
penicillamine
-
treated
patients
,
pemphigus
foliaceus
is
more
common
____________________
pemphigus
vulgaris
,
with
an
approximate
ratio
of
4
:
1
.
