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1. Pharmacologic treatment of epididymitis may include the following:
2. In addition to antibiotics (except in viral epididymitis), the mainstays of supportive therapy for acute epididymitis and orchitis are as follows:
3. Surgical options include the following:
4. Complications associated with acute epididymitis and bacterial orchitis include the following:

Fertility problems

In prepubertal patients with epididymitis, antibiotic therapy only for young infants and those with pyuria or positive urine culture findings

Testicular atrophy

Analgesics, including nerve blocks

Ice packs

Testicular infarction: Cord swelling can limit testicular artery blood flow

Scrotal abscess and pyocele

Epididymotomy: Infrequently performed in patients with acute suppurative epididymitis

Recurrence, chronic epididymitis, and orchialgia

Cutaneous fistulization from rupture of an abscess through the tunica vaginalis (seen especially in tuberculosis)

When treating epididymitis secondary to Chlamydia trachomatis or Neisseria gonorrhoeae, treatment of all sexual partners

Scrotal support and elevation

Anti-inflammatory agents

In chronic epididymitis, a 4- to 6-week trial of antibiotics effective against bacterial pathogens (especially chlamydiae)

Skeletonization of the spermatic cord via subinguinal varicocelectomy: Performed in rare cases of refractory pain due to chronic epididymitis and orchialgia

Reduction in physical activity

Orchiectomy: Indicated only for patients with unrelenting epididymal pain

Avoidance of urethral instrumentation

Sitz baths

Epididymectomy: Typically reserved for refractory cases