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1. The following are investigative studies to detect a clinically suspected focal infection, the presence of a clinically occult focal infection, and complications of sepsis and septic shock:
2. The following radiologic studies, as indicated, may be used to evaluate patients with suspected severe sepsis and septic shock:

Renal and hepatic function tests (eg, creatinine, blood urea nitrogen, bilirubin, alkaline phosphatase, alanine aminotransferase, aspartate aminotransferase, albumin, lipase)

Blood chemistry (eg, sodium, chloride, magnesium, calcium, phosphate, glucose, lactate)

Blood cultures

Urinalysis and urine cultures

Abdominal ultrasonography

Complete blood count with differential

Coagulation studies (eg, prothrombin time [PT], activated partial thromboplastin time [aPTT], fibrinogen levels)

Computed tomography of the abdomen or head

Chest, abdominal, or extremity radiography

Gram stain and culture of secretions and tissue