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1. GLP-1 Receptor Agonist
2. SGLT-2 Inhibitor

Avoid in patients with impaired kidney function

In patients with Type 2 DM and established HF, this may be considered to reduce risk of HF hospitalization

Increases loss of glucose in urine

Stimulates insulin secretion

Decreases appetite

Slows gastric emptying

Reduces glucose reabsorption

Recommended to reduce CV risk in patient with Type 2 DM & established ASCVD

Suppresses glucagon secretion

Trulicity, Byetta, Bydureon, Victoza, Ozempic

Invokana, Farxiga, Jardiance

Use with caution in patients receiving higher dose diuretics