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The hormones produced by the hypothalamus that control the anterior pituitary travel in a unique circulatory pathway . These hormones enter the hypothalamic capillaries , which empty into hypothalamic ____________________ . Instead of returning to the heart as other veins do , the hypothalamic veins empty directly into pituitary ____________________ . This type of pathway is called a ____________________ ____________________ , and it allows hypothalamic hormones to be delivered directly to the pituitary gland found below it , without ever having to enter the general circulation .

Four of the hormones produced by the anterior pituitary have an effect on other glands . Thyroid - stimulating hormone stimulates the thyroid to produce the ____________________ hormones , and ____________________ hormone stimulates the adrenal cortex to produce its hormones . There are actually two gonadotropic hormones or gonadotropins , which work on the ____________________ . Follicle - stimulating hormone and ____________________ hormone stimulate the production of gametes and sex hormones in the male testes and the female ____________________ . The hypothalamus , the anterior pituitary , and other glands controlled by the anterior pituitary are all involved in self - regulating ____________________ feedback mechanisms that maintain stable conditions . In each instance , the blood level of the last hormone in the sequence exerts negative feedback control over the secretion of the first two hormones .

Other hormones produced by the anterior pituitary do not affect other endocrine glands . In women , ____________________ is produced beginning at about the fifth month of pregnancy and is produced in quantity after childbirth . It causes the mammary glands in the breasts to develop and produce ____________________ . It also plays a role in carbohydrate and fat metabolism .

____________________ hormone stimulates protein synthesis within cartilage , bone , and muscle . It stimulates the rate at which amino acids enter cells and protein synthesis occurs . It also promotes the breakdown of fat , called ____________________ ____________________ , so that body cells can utilize fat instead of glucose for energy . In addition , GH produced by the anterior pituitary affects our height , because GH directly stimulates the osteoblast cells in the growth plates of long bones . The quantity of GH produced is greatest during ____________________ and adolescence , when most body growth is occurring .