inhibit elongation, intercalated near G residue
makes antibodies to DNA and SnRNA-binding protein
a-amanitin
Amanita Phalloides
patient who present with flushing, high blood calcitonin level, exhibit alternative mRNA splicing
alpha helix, zinc finger, helix turn helix catalyze histone acetylation/deacetylation, recruit coactivators and corepressors.
synthesis hnRNA (nuclear RNA)
Betal Thalassemia in Ch 11
Alpha Thalassemia Both fetus (HbF) and (HbA), defective remodeling and spacing protein
catalyze synthesis of rRNA
RNA polymerase II
Butterfly shaped rash. Systemic Lupus Erythematosus
RNA polymerase I
Actinomycin D
Defect on Ch. 16
result from hnRNA Splicing defect, hnRNA Cap site defect, poly(A) signal defect.
Medullary Thyroid Cancer
Death cap mushroom inhibit pol II and III, microfilament are stabilized . gastric lavage.
inhibit RNA pol II
Transcription Factors
