Matching Pairs 1.2.7 Bone RemodelingOnline version Calcium feedback and steps of bone remodeling by Laura Roy 1 Parathyroid 2 Osteoclast 3 Parathyroid hormone 4 Hypocalcemia 5 Step 2 of Bone Remodeling 6 Thyroid gland 7 Osteoblast 8 Calcitonin 9 Step 3 of Bone Remodeling 10 Step 4 of Bone Remodeling 11 Step 1 of Bone Remodeling 12 Hypercalcemia Releases parathyroid hormone Fibrocartilaginous callus formation. Connective tissue stem cells & capillary blood vessels penetrate. Phagocytes clear away junk. Cartilage and blood vessels start to form to create new bone Bony Callus Formation. Takes several weeks to months. Osteoclasts break down fibrous cartilage Osteoblasts lay new bone matrix, made of osteocytes. Bone is MOSTLY healed at this stage High calcium levels A hormone that increases Ca in the blood by stimulating bone to be broken down. Builds bone Low calcium levels Releases calcitonin Breaks down bone A hematoma is a “blood tumor” that forms at the site of the break This painful, swollen area fills with blood from the broken blood vessels A hormone that lowers Ca in blood by stimulating bone to be built. Bone Remodeling - Compact bone replaces woven bone. Internal callus removed. Medullary cavity is restored