Fill in the Blanks Acne treatmentOnline version Acne treatment by niamh shillock 1 First line treatment of acne should include the following advice ; use a non - synthetic detergent cleansing product daily on acne - prone areas , remove at the end of the day , and avoid oil - based or comedogenic products . Also avoid or scratching of lesions . Photodynamic therapy can be used in which light is used to kill the acne causing bacteria . For mild acne topical peroxide with clindamycin is used . For acne a combination of topical adapalene ( contains acid ) with benzoyl peroxide ( anti - ) , with antibiotics such as lymecycline or doxycycline , or topical azelaic acid ( an antikeratinizing agent which also keratinocyte proliferation ) with oral . If patients aren't suitable for combines treatment benzoyl peroxide alone is used . Second line , if the patient is to first line treatment , includes oral isotretinoin ( ) which shrinks sebaceous which also leads to a in bacteria and is anti - , but it has many effects . health services referrals may also be appropriate due to the impact .
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