Froggy Jumps PIWI RNA QuizOnline version Test your knowledge about PIWI RNA with these questions! by Leyla Cufurovic 1 How does PIWI RNA primarily silence transposable elements? a Promoting their transcription b Inducing DNA mutations c Cleaving their transcripts 2 Which of the following organisms is PIWI RNA pathway highly conserved in? a Plants b Bacteria c Insects 3 What does PIWI stand for? a P-element Induced Wimpy testis b PIWI-interacting RNA c Protein Inhibitor of Wingless 4 What is the main function of PIWI RNA? a Promoting gene expression b Silencing transposable elements c Enhancing DNA repair 5 What is the size range of PIWI RNA molecules? a 24-32 nucleotides b 50-100 nucleotides c 10-15 nucleotides 6 Which organism was PIWI RNA first discovered in? a Homo sapiens b Drosophila melanogaster c Escherichia coli 7 What is the role of PIWI RNA in germ cells? a Controlling cell division b Maintaining genome integrity c Regulating metabolism 8 Which protein family does PIWI RNA belong to? a Histone b Argonaute c Kinesin 9 What is the function of PIWI proteins? a Catalyzing DNA replication b Binding to PIWI RNA and guiding gene silencing c Transporting proteins 10 What is the mechanism of PIWI RNA-mediated gene silencing? a Activation of target genes b Cleavage or translational repression of target mRNAs c Enhancement of mRNA stability 11 The complex formed by PIWI RNA and PIWI proteins is known as: a RISC b piRNA-PIWI c piRISC 12 Which of the following is a conserved feature of PIWI RNA across different organisms? a Regulation of transposable elements b Varying lengths of PIWI RNA molecules c Involvement in immune responses 13 In which type of cells is PIWI RNA primarily involved? a Neuronal cells b Stem cells c Germ cells
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