Matching Pairs Meds affecting musculoskeletal & digestive systemsOnline version Match each Subcategory with its action or use by Kristie Borgheiinck 1 Increases bone density 2 suppress gastric acid secretion by inhibiting the acid pump system of the gastric mucosa 3 induce vomitting 4 NSAIDs :an enzyme that triggers pain & inflammation 5 reduce acid secretion or protect gastric mucosa 6 Produce immunosuppression 7 reduces flatus 8 reduce the inflammatory response by repressing the expression of pro-inflammatory immune cells 9 Corticosteroid: protein made by certain immune & non-immune cells that has an effect on immune system 10 inhibit uric acid production 11 reduce the acidity of the stomach 12 inhibit neurotransmitters that stimulate vomiting 13 increase motility of upper GI tract w/o increasing production of gastric secretions 14 treatment of various acute painful musculoskeletal conditions 15 anti inflammatory 16 analgesic and antipyreticactivity but does not have anti-inflammatory action; 17 anti-inflammatory, anti-pyretic, and analgesic actions 18 block the histamine (H2) receptors in stomach, reduces gastric acid 19 increase digestion of fats 20 prolongs bleeding time by inhibiting the aggregation of platelets 21 decrease intestinal peristalsis Uric acid inhibitors Non-salicylate analgesic Cytokine Proton pump inhibitor DMARDs Antacid Histamine (H2) receptor antagonists Skeletal Muscle Relaxants Salicylates Corticosteroids COX-2 GI stimulants Misc. acid reducers pancreatic enzyme NSAIDs antiflatulents antiemetics antidiarrheal emetics Bone resorption inhibitors aminosalicylates 1 inhibit prostagaldines 2 used for heartburn, acid indigestion, sour stomach, GERD, PUD, gastric ulcers 3 Used for peptic ulcers 4 Used for GERD, gastroparesis (gastric stasis in diabetics), esophagitis, cancer chemotherapy (antiemetic to inhibit CTZ), postop to prevent ileus 5 treatment of osteoporosis, hypercalcemia of malignant diseases & bony metastasis with solid tumors, & Paget's disease 6 uses heartburn, acid indigestion, GERD, gastric/duodenal ulcers, & hypersecretory conditions 7 used for post op gas distension & air swallowing, dyspepsia, peptic ulcer, IBS, diverticulosis, nonspecific pruritis w/ dialysis, antidote for poison 8 action may be due to sedative activity 9 used for accidental ingestion of poison or drug OD; guidelines established by the FDA 10 used for treatment & prevention of gout 11 treats autoimmune disorders: RA, SLE, ankylosing spondylitis, mixed connective tissue disease, Crohn's, ulcerative colitis 12 does not inhibit platelet aggregation 13 Management of chronic alcoholism in patients who require or desire an enforced state of sobriety 14 used for pancreatic insufficiency with chronic pancreatitis, cystic fibrosis, GI bypass surgery, ductal obstruction secondary to tumor 15 Used for gastric, duodenal (esp. Hellicobactor pylori infections), GERD, erosive esophagitis, & pathological hyper-secretory conditions 16 used for Crohn's, ulcerative colitis, & other inflammatory conditions 17 treats N/V/D, typically used prophalactically 18 used to treat diarrhea 19 used for short term relief or prevention of constipation Bone resorption inhibitors Uric acid inhibitors aminosalicylates NSAIDs GI stimulants DMARDs antidiarrheal antialcoholic antiflatulents laxatives pancreatic enzyme Skeletal Muscle Relaxants Non-salicylate analgesic Proton pump inhibitor antacid Misc. acid reducers antiemetics emetics Histamine (H2) receptor antagonists