Fill in the Blanks Fill in the Blanks: Krebs CycleOnline version Test your knowledge of the Krebs cycle by filling in the missing words in this interactive game! by Bio Innovators 1 transport chain matrix Tricarboxylic acid Krebs cycle NADH electron FADH2 is also known as Citric acid cycle or cycle . It occurs in the of mitochondria to provide in the form of and that are used in electron . 2 pyruvate oxidation isocitrate addition Condensation oxaloacetate, OAA rearranged CoA citrate Isomerization Citrate removal 1 . Acetyl - CoA from removes group . The remaining acetyl combines with to form . 2 . is then to its isomer , by the of one water molecule and of one water molecule . 3 reduced transferring 5-carbon H CO2 ketoglutarate decarboxylation NAD 3 . Oxidative decarboxylation Isocitrate loses a molecule of , forming a molecule ( ) . The remaining 5 - carbon is oxidized into ? - , by their electrons and + to NAD + . + is to NADH + H + . 4 NADH oxidized Coenzyme A succinyl CoA 4C molecule ketoglutarate CO2 4 . Oxidative decarboxylation ? - lose a molecule of forming a 4C molecule . The remaining is before combining with , to form . NAD + is reduced to + H + . 5 FAD FADH CoA succinate Substrate level GTP ATP phosphate group ADP GTP FAD two hydrogen atoms Succinate energy phosphorylation fumarate 5 . phosphorylation Succinyl - CoA loses and converted to . The released is used in the of GDP to form . then transfer its to to form . 6 . Oxidation is oxidized to , by transferring to . is reduced to . 6 regenerated NADH malate Fumarate Reduction Malate oxaloacetate rearranged oxidized water molecule 7 . Hydration is into by addition of one . 8 . Oxidation is . of NAD + to + H + occurs and is .