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Fill in the Blanks: Krebs Cycle

Fill in the Blanks

Test your knowledge of the Krebs cycle by filling in the missing words in this interactive game!

Download the paper version to play

Recommended age: 18 years old
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Malaysia

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Fill in the Blanks

Fill in the Blanks: Krebs CycleOnline version

Test your knowledge of the Krebs cycle by filling in the missing words in this interactive game!

by Bio Innovators
1

electron NADH transport chain Krebs cycle matrix Tricarboxylic acid FADH2

is also known as Citric acid cycle or cycle . It occurs in the of mitochondria to provide in the form of and that are used in electron .

2

oxaloacetate, OAA Citrate isocitrate pyruvate oxidation rearranged removal Isomerization citrate CoA Condensation addition

1 .
Acetyl - CoA from removes group . The remaining acetyl combines with to form .

2 .
is then to its isomer , by the of one water molecule and of one water molecule .

3

NAD 5-carbon decarboxylation transferring CO2 ketoglutarate reduced H

3 . Oxidative decarboxylation
Isocitrate loses a molecule of , forming a molecule ( ) . The remaining 5 - carbon is oxidized into ? - , by their electrons and + to NAD + . + is to NADH + H + .

4

ketoglutarate succinyl CoA Coenzyme A NADH 4C molecule oxidized CO2

4 . Oxidative decarboxylation
? - lose a molecule of forming a 4C molecule . The remaining is before combining with , to form . NAD + is reduced to + H + .

5

FAD fumarate GTP phosphate group GTP energy succinate Substrate level ATP FADH phosphorylation ADP Succinate two hydrogen atoms CoA FAD

5 . phosphorylation
Succinyl - CoA loses and converted to . The released is used in the of GDP to form . then transfer its to to form .

6 . Oxidation
is oxidized to , by transferring to . is reduced to .

6

Fumarate oxaloacetate rearranged malate Malate regenerated oxidized water molecule Reduction NADH

7 . Hydration
is into by addition of one .

8 . Oxidation
is . of NAD + to + H + occurs and is .

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