Matching Pairs Cholesterol pharmacologyOnline version Cholesterol pharmacology by Ashleigh Pell 1 statin warning 2 statin with less drug interactions 3 statin indication 4 with less cholesterol synthesis, what does the liver do? 5 What statins do, and where 6 statin side effects 7 standard statin 8 What does the enzyme HMG-CoA do? 9 most potent statin myalgia/headache/GI symptoms increases hepatic synthesis of cholesterol atorvastatin simvastatin inhibit HMG-CoA reductase in the liver high lipids / LDL pravastatin Grapefruit inhibits cytochrome P450, increasing statin bioavailability. increases the uptake of low-density lipoprotein (LDL) from the blood 1 fenofibrate caution 2 Alirocumab inhibits 3 alirocumab indication 4 ezetimisbe side effect 5 fenofibrate side effects 6 fenofibrate activates 7 fenofibrate contra-indication 8 Alirocumab side effects 9 fenofibrate causes lipolysis because 10 ezetimibe inhibits 11 Fenofibrate indication flu-like symptoms GI upset/vomiting familial hypercholesterolaemia, high risk, statins and ezetimibe ineffective myotoxicity if improper dose or renal impairment. gall bladder disease, pancreatitis inhibits PCSK9, a liver protein that regulates/breaks down LDL receptors intestinal cholesterol absorption weakness/GI upset/headaches PPARα's genes code for peroxisomes which participate in lipolysis high serum triglycerides nuclear receptor PPARα which begins gene transcription and translation
New game