Pathophysiology game (CHF, DM2, CKD, Hypothyroidism)Online version Test your knowledge of nursing diagnoses by correctly ordering them based on their specificity from general to specific. by Teisha Vaughn 1 Order the elements based on the sequence of physiological changes that occur in the body during the progression of CHF. Myocardial injury Decreased cardiac output Increased cardiac workload Fluid retention Heart remodeling Activation of neurohormonal systems 2 Order the elements based on the progression of pathophysiological changes in chronic kidney disease from initial to advanced stages. Glomerular hyperfiltration End-stage renal disease Compensatory hypertrophy of remaining nephrons Decreased nephron function Tubulointerstitial fibrosis Development of glomerulosclerosis 3 Order the elements based on the sequence of physiological changes that occur in the body leading to Type 2 Diabetes. Development of complications related to diabetes Insulin resistance develops in peripheral tissues Increased insulin production by the pancreas Elevated blood glucose levels Dysfunction of pancreatic beta cells Increased hepatic glucose production 4 Order the elements based on the sequence of events in the pathophysiology of diabetic foot ulcers, from initial risk factors to ulcer formation. Ulcer formation Foot deformities Peripheral neuropathy Skin breakdown Poor circulation Infection 5 Order the elements based on the sequence of physiological changes that occur in the body due to hypothyroidism, from initial effects to final consequences. Accumulation of glycosaminoglycans in tissues Reduced metabolic rate Increased levels of thyroid-stimulating hormone (TSH) Manifestation of clinical symptoms such as fatigue and weight gain Decreased energy production and utilization Decreased production of thyroid hormones