The Pathophysiology Puzzle 2 (Stroke, CAncer, NSTEMI. STEMI, HTN)Online version Test your knowledge of cancer pathophysiology by correctly ordering key concepts related to its development and progression. by Teisha Vaughn 1 Order the elements based on the sequence of events in the progression of cancer development. Metastasis to distant sites Initiation of genetic mutations Invasion of surrounding tissues Promotion of cell proliferation Progression to malignancy Angiogenesis to support tumor growth 2 Order the elements based on the sequence of events leading to NSTEMI, from initial trigger to final outcome. Partial occlusion of the coronary artery Plaque rupture or erosion Platelet activation and aggregation Myocardial ischemia Cellular injury and necrosis Formation of a thrombus 3 Order the elements based on the sequence of physiological events that occur during a STEMI, from the initial trigger to the final consequences. Release of inflammatory mediators Myocardial cell injury Complications such as heart failure or arrhythmias Necrosis of myocardial tissue Ischemia of myocardial tissue Coronary artery occlusion 4 Order the elements based on the sequence of pathophysiological events leading to a cerebrovascular accident. Decreased blood flow to the brain Release of excitatory neurotransmitters Initial vascular occlusion or rupture Ischemic or hemorrhagic damage to brain tissue Potential recovery or chronic deficits Inflammatory response and cell death
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