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Metabolismo de lípidos

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Metabolismo de lípidos

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About this activity

Objetivo, repasar los conceptos vistos en clase el día de hoy.

Created by

GUEVARA PALOMA
GUEVARA PALOMA
Argentina

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Metabolismo de lípidosOnline version

Objetivo, repasar los conceptos vistos en clase el día de hoy.

by GUEVARA PALOMA
1 Realiza el transporte reverso de colesterol 2 Transporta trigliceridos de la dieta 3 Tienen receptores para apo B100 4 Tiene receptores para apo E 5 Es atacado por una lipasa hepatica 6 Transporta mayormente colesterol esterificado 7 Es el producto de la acción de la AG sintetasa 8 Proviene de la accion de la Acetil-CoA carboxilasa 9 Sale al citosol por la lanzadera del citrato 10 Esta via no tiene punto de regulacion 11 Proviene de la glucolisis 12 Punto de regulación de la síntesis de colesterol 13 Esta vía es inducida por insulina

Explicación

Junto con la transferencia de apo C y apo E, es una de las funciones del colesterol.

Los Qm realizan el transporte de lípidos exógenos

Permiten el ingreso de LDL a los tejidos extra hepáticos

Permite el ingreso de IDL, VLDL y Qm remanente

Asi es vaciado de TAGs y convertido en LDL

El acido palmitico o palmitato es el unico AG capaz de ser sintetizado por AG sintetasa

El malonil CoA se forma previamente en el citosol para poder ser agregado a un AG en construcción

El Acetil Coa es exportado de la mitocondria por una lanzadera

Su velocidad se modula por la disponibilidad de sustrato

En tejido adiposo, la DHAP se utiliza para sintetizar glicerol y luego TAGs

Tiene modulación covalente, modula la síntesis de colesterol

En situación de saciedad se activa la HMGCoA reductasa, aumentando la síntesis de colesterol