Froggy Jumps Pharmacogenomics QuizOnline version Genetics-informed drug knowledge by rajshri naik 1 What is an SNP in pharmacogenomics? a A single nucleotide difference in the genome b A protein produced by the liver c A type of drug transporter 2 Why are SNPs useful in drug testing? a They always cause disease b They only occur in non-coding regions c They occur in many genes and can affect drug response 3 What is one advantage of SNP detection methods? a They need radioactive labeling b They require live animals c They can be typed without gel electrophoresis 4 What does RFLP stand for in genetic mapping? a Regional Functional Loci Polymorphism b Restriction Fragment Length Polymorphism c Rapid Fluorescent Lipid Polymorphism 5 Which mapping approach uses chromosomes as markers? a Clinical mapping b Genetic mapping c Physical mapping 6 What is a key use of linkage analysis in pharmacology? a To synthesize drugs b To map weather patterns c To link traits or markers to drug-response genes 7 What does a LOD score indicate in linkage analysis? a Drug potency b Evidence for or against linkage between markers c Side-effect frequency 8 What is a common feature of SSLPs (VNTRs/STRs)? a Only found in bacterial genomes b Repeat units that vary in copy number c Always 3 base pairs long 9 How can SNPs be detected more rapidly than some methods? a By measuring drug weight in plasma b Using oligonucleotide hybridization without gel c By sequencing entire genomes every time 10 Which mapping technique visualizes a marker on intact chromosomes? a Mass spectrometry b CRISPR editing c Fluorescent in situ hybridization (FISH)
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