Biomedical Research MethodsOnline version Methods used in biomedical research by Amanda Hyatt 1 Research Methods 2 Descriptions of Research Methods Chemical, mechanical, mathematical, and computer simulations In Vitro Animal Models Human studies Epidemiological Studies used in the preliminary stages of research to understand and simulate living systems studies the biological process in an artificial environment Used to study the ineractions of a substance when introduced to a complex living system Used most often in developing drugs to establish the safety and effectiveness of drugs used to study the spread and occurence of diseases