Matching Pairs Week 1 CardiologyOnline version Describe the epidemiology of acute coronary syndromes and stable coronary artery disease Discuss the prognosis and impact of ischaemic heart disease on daily life. Describe how good management can improve both aspects Explain how the cardiovascular system adapts to exercise by Hannah Barton 1 Aspirin for secondary prevention can reduce risk of MI, stroke or vascular death by how much…? 2 How is blood pressure calculated? 3 Why are blood pressure changes minimal during exercise? 4 What are some risk factors for the acute coronary syndromes? 5 What is coronary artery disease an umbrella term for? 6 What is increased preload a result of? 7 How can stable and unstable angina be differentiated from the history? 8 How many patients experiencing an acute MI die before reaching the hospital? 9 What is variant angina? 10 Why must splenic contraction increase during exercise? 11 What is increased contractility of the heart a result of? 12 How can stable angina progress to unstable angina (acute coronary syndrome) 13 How is reperfusion therapy useful in MI? Increased sympathetic nervous system activity Increased use of skeletal muscle pumps and peripheral vasoconstriction means Angina without the presence of physical plaques; caused by intense vasospasm Reduced pulmonary and systemic vascular resistance to blood flow Cardiac output x systemic vascular resistance Reduces infarct size and can help to prevent death from heart failure and ventricular arrhythmias 33% Up to 30% of RBCs are stored here and so increased contraction ejects more of these into blood stream to transport oxygen Conditions involving atherosclerosis restricting blood flow to the heart, causing ischaemia Ageing, hypertension, hypercholesteremia, smoking, obesity Whether or not they are provoked by exercise 25% The plaque narrowing the lumen ruptures causing platelet aggregation, thrombus formation and unopposed vasoconstriction