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3. Hormone Action

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Explain the mechanism of non-steroid hormone action

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3. Hormone ActionOnline version

Explain the mechanism of non-steroid hormone action

by Helmina Kmrzmn
1

phosphorylation secondary hormone dissociate kinase adenylyl G ATP cyclase first lipid receptor

Non - steroid hormones are not soluble in , therefore unable to enter the cell . They bind to the protein on the surface of the cell's plasma membrane , forming the - receptor complex . The hormone acts as the messenger . Hormone - receptor complex will activate the - proteins that are found within the plasma membrane .
The activated G - proteins will activate an enzyme found in the plasma membrane , the . This will initiate the conversion of into the cAMP , which will act as the messenger . This process takes place on the inside of the plasma membrane . Second messenger cAMP will diffuse across the cytoplasm and bind to protein , therefore activating it . Enzyme kinase functions by conducting , which is the adding of phosphate group to specific cellular proteins .
After activating the second messenger , the hormone from the receptor . Hormone will be transported to other target cells , or degraded if no longer required .

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