Matching Pairs TBI TerminologyOnline version Watch the YouTube video "How Brain Damage Works" and then match the terms from the video to their definitions or descriptions. by Cindy Gibson 1 Primary injury 2 Coup-Contracoup Injury 3 Ischemia 4 Hemorrhage 5 Intracranial Pressure (ICP) 6 Apoptosis 7 Diffuse Axonal Injury 8 Secondary Injury 9 Necrosis 10 Edema 11 Calpain 12 Glutamate Physical impact of the brain at the time of injury. Swelling of the brain that causes it to push against the restraints of the skull Bleeding due to ruptured blood vessel(s) cell suicide The brain strikes the inside of the skull in two opposing locations. Delayed brain pathologies that occur minutes to days after the initial brain impact. Mechanical tearing and shearing of axons due to injury Cell death at sites of injury that spreads to surrounding neurons due to enzymes released by dying cells Reduced blood flow Activated by calcium, this enzyme triggers breakdown of the cell's membrane An excitatory neurotransmitter that triggers overexcitation in neurons when it leaks out of cells in large amounts. Fluid accumulation