Matching Pairs TBI TerminologyOnline version Watch the YouTube video "How Brain Damage Works" and then match the terms from the video to their definitions or descriptions. by Cindy Gibson 1 Necrosis 2 Hemorrhage 3 Apoptosis 4 Coup-Contracoup Injury 5 Edema 6 Secondary Injury 7 Primary injury 8 Glutamate 9 Diffuse Axonal Injury 10 Ischemia 11 Calpain 12 Intracranial Pressure (ICP) Bleeding due to ruptured blood vessel(s) An excitatory neurotransmitter that triggers overexcitation in neurons when it leaks out of cells in large amounts. Delayed brain pathologies that occur minutes to days after the initial brain impact. cell suicide The brain strikes the inside of the skull in two opposing locations. Cell death at sites of injury that spreads to surrounding neurons due to enzymes released by dying cells Physical impact of the brain at the time of injury. Activated by calcium, this enzyme triggers breakdown of the cell's membrane Mechanical tearing and shearing of axons due to injury Reduced blood flow Swelling of the brain that causes it to push against the restraints of the skull Fluid accumulation