Matching Pairs TBI TerminologyOnline version Watch the YouTube video "How Brain Damage Works" and then match the terms from the video to their definitions or descriptions. by Cindy Gibson 1 Calpain 2 Edema 3 Apoptosis 4 Hemorrhage 5 Intracranial Pressure (ICP) 6 Primary injury 7 Ischemia 8 Necrosis 9 Glutamate 10 Secondary Injury 11 Coup-Contracoup Injury 12 Diffuse Axonal Injury Bleeding due to ruptured blood vessel(s) Mechanical tearing and shearing of axons due to injury An excitatory neurotransmitter that triggers overexcitation in neurons when it leaks out of cells in large amounts. Delayed brain pathologies that occur minutes to days after the initial brain impact. Activated by calcium, this enzyme triggers breakdown of the cell's membrane The brain strikes the inside of the skull in two opposing locations. Cell death at sites of injury that spreads to surrounding neurons due to enzymes released by dying cells Swelling of the brain that causes it to push against the restraints of the skull cell suicide Physical impact of the brain at the time of injury. Fluid accumulation Reduced blood flow