Necrosis
Apoptosis
Glutamate
Calpain
Secondary Injury
Diffuse Axonal Injury
Intracranial Pressure (ICP)
Edema
Hemorrhage
Primary injury
Ischemia
Coup-Contracoup Injury
Mechanical tearing and shearing of axons due to injury
An excitatory neurotransmitter that triggers overexcitation in neurons when it leaks out of cells in large amounts.
Swelling of the brain that causes it to push against the restraints of the skull
Fluid accumulation
Bleeding due to ruptured blood vessel(s)
Reduced blood flow
cell suicide
The brain strikes the inside of the skull in two opposing locations.
Delayed brain pathologies that occur minutes to days after the initial brain impact.
Activated by calcium, this enzyme triggers breakdown of the cell's membrane
Physical impact of the brain at the time of injury.
Cell death at sites of injury that spreads to surrounding neurons due to enzymes released by dying cells
