Matching Pairs TBI TerminologyOnline version Watch the YouTube video "How Brain Damage Works" and then match the terms from the video to their definitions or descriptions. by Cindy Gibson 1 Necrosis 2 Secondary Injury 3 Primary injury 4 Ischemia 5 Hemorrhage 6 Glutamate 7 Apoptosis 8 Coup-Contracoup Injury 9 Intracranial Pressure (ICP) 10 Calpain 11 Diffuse Axonal Injury 12 Edema An excitatory neurotransmitter that triggers overexcitation in neurons when it leaks out of cells in large amounts. The brain strikes the inside of the skull in two opposing locations. cell suicide Fluid accumulation Bleeding due to ruptured blood vessel(s) Swelling of the brain that causes it to push against the restraints of the skull Delayed brain pathologies that occur minutes to days after the initial brain impact. Cell death at sites of injury that spreads to surrounding neurons due to enzymes released by dying cells Reduced blood flow Mechanical tearing and shearing of axons due to injury Physical impact of the brain at the time of injury. Activated by calcium, this enzyme triggers breakdown of the cell's membrane