Matching Pairs TBI TerminologyOnline version Watch the YouTube video "How Brain Damage Works" and then match the terms from the video to their definitions or descriptions. by Cindy Gibson 1 Necrosis 2 Edema 3 Primary injury 4 Diffuse Axonal Injury 5 Glutamate 6 Secondary Injury 7 Calpain 8 Intracranial Pressure (ICP) 9 Apoptosis 10 Coup-Contracoup Injury 11 Ischemia 12 Hemorrhage Bleeding due to ruptured blood vessel(s) Mechanical tearing and shearing of axons due to injury Swelling of the brain that causes it to push against the restraints of the skull The brain strikes the inside of the skull in two opposing locations. cell suicide Activated by calcium, this enzyme triggers breakdown of the cell's membrane Delayed brain pathologies that occur minutes to days after the initial brain impact. Reduced blood flow Physical impact of the brain at the time of injury. An excitatory neurotransmitter that triggers overexcitation in neurons when it leaks out of cells in large amounts. Cell death at sites of injury that spreads to surrounding neurons due to enzymes released by dying cells Fluid accumulation