Matching Pairs TBI TerminologyOnline version Watch the YouTube video "How Brain Damage Works" and then match the terms from the video to their definitions or descriptions. by Cindy Gibson 1 Primary injury 2 Hemorrhage 3 Intracranial Pressure (ICP) 4 Diffuse Axonal Injury 5 Coup-Contracoup Injury 6 Edema 7 Necrosis 8 Glutamate 9 Apoptosis 10 Ischemia 11 Secondary Injury 12 Calpain Bleeding due to ruptured blood vessel(s) Physical impact of the brain at the time of injury. Delayed brain pathologies that occur minutes to days after the initial brain impact. cell suicide Fluid accumulation Cell death at sites of injury that spreads to surrounding neurons due to enzymes released by dying cells Reduced blood flow Mechanical tearing and shearing of axons due to injury The brain strikes the inside of the skull in two opposing locations. Swelling of the brain that causes it to push against the restraints of the skull Activated by calcium, this enzyme triggers breakdown of the cell's membrane An excitatory neurotransmitter that triggers overexcitation in neurons when it leaks out of cells in large amounts.