Matching Pairs TBI TerminologyOnline version Watch the YouTube video "How Brain Damage Works" and then match the terms from the video to their definitions or descriptions. by Cindy Gibson 1 Intracranial Pressure (ICP) 2 Diffuse Axonal Injury 3 Apoptosis 4 Ischemia 5 Necrosis 6 Hemorrhage 7 Glutamate 8 Coup-Contracoup Injury 9 Secondary Injury 10 Calpain 11 Edema 12 Primary injury Activated by calcium, this enzyme triggers breakdown of the cell's membrane cell suicide The brain strikes the inside of the skull in two opposing locations. Physical impact of the brain at the time of injury. Delayed brain pathologies that occur minutes to days after the initial brain impact. Swelling of the brain that causes it to push against the restraints of the skull Cell death at sites of injury that spreads to surrounding neurons due to enzymes released by dying cells Fluid accumulation Mechanical tearing and shearing of axons due to injury An excitatory neurotransmitter that triggers overexcitation in neurons when it leaks out of cells in large amounts. Reduced blood flow Bleeding due to ruptured blood vessel(s)