Matching Pairs NUR 341 Mechanism of action 1Online version Match by Tamara Garcia 1 Cephalexin 2 Atorvastatin Simvastatin 3 Clopidogrel 4 Furosemide 5 Acetaminophen/codeine Acetaminophen/oxycodone Hydrocodone/Acetaminophen Hydromorphone 6 Heparin 7 Amlodipine Blocks the P2Y12 component of ADP receptors on the platelet surface, which prevents activation of the GPIIb/IIIa receptor complex, thereby reducing platelet aggregation. Potentiates the action of antithrombin III and thereby inactivates thrombin and prevents the conversion of fibrinogen to fibrin. Inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, the rate-limiting enzyme in cholesterol synthesis; helps reduce inflammation at the site of the coronary plaque, inhibits platelet aggregation, and has anticoagulant effects. Inhibits pain pathways in the CNS. Inhibits reabsorption of sodium and chloride in the ascending loop of Henle and proximal and distal renal tubules, interfering with the chloride-binding cotransport system, thus causing its natriuretic effect. Inhibits calcium ion from entering the “slow channels” or select voltage-sensitive areas of vascular smooth muscle and myocardium during depolarization, producing a relaxation of coronary vascular smooth muscle and coronary vasodilation; it also increases myocardial oxygen delivery. Inhibits bacterial cell wall synthesis by binding to one or more of the penicillin-binding proteins (PBPs).
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