Matching Pairs Etiology, Pathogenesis and Definition for Exam 2Online version Skin, Respiratory, Cardio and Neuro Pathology by Jessica Petry 1 Bilateral, symmetric necrosis (malacia) of the basal ganglia, internal capsule, thalamus, and substantia nigra 2 Edema disease of recently weaned pigs on high-protein rations 3 Bacteria in poorly fermented silage that impacts Cranial Nerve V 4 Histophilus somni 5 Nigropallidal encephalomalacia 6 Visceral Gout 7 Polioencephalomalacia 8 Hansen type 2 9 Mycotoxic leukoencephalomalacia 10 Hansen type 1 Clostridium perfringens Type D Prolonged ingestion of yellow star thistle or Russian knapweed Thrombotic meningoencephalitis, intralesional bacterial colonies Mycotoxin = fumonisin B1 release of nucleus pulp material into the spinal canal, resulting in compression protrusion of the annulus fibrosus into the spinal canal, resulting in compression (stays encapsulated) Thiamine (Vitamin B1) deficiency, Sulfur/Lead/Salt toxicity Listeria monocytogenes High protein diet, Vitamin A deficienct Escherichia coli 1 Purple mint toxin 2 Equine Multinodular Pulmonary Fibrosis 3 Porcine Contagious Pleuropneumonia 4 Moldy Sweet Potato Toxin 5 Ovine Progressive Pneumonia 6 Lush Green Grass toxin 7 Rhodococcus Pneumonia of Foals 8 Enzootic Pneumonia of Pigs 9 Caprine Arthritis Encephalitis 10 Shipping Fever of Cattle Equine gamma herpesvirus 5 CAEV Mycoplasma hyopneumoniae Visna-Maedi Virus Mannheimia haemolytica Ketones Rhodococcus equi tryptophan, converted to 3-methyl-indole Fusarium solani produces 4-ipomeanol Actinobacillus pleuropneumoniae 1 Acute Bovine Pulmonary Edema and Emphysema 2 Arteritis 3 Non-Progressive Form of porcine atrophic rhinitis 4 Infectious bovine rhinotracheitis 5 Necrotic Laryngitis 6 Traumatic reticulopericarditis (TRP): hardware disease 7 Artherosclerosis 8 Progressive Form of porcine atrophic rhinitis 9 Thrombophlebitis 10 Strangles Dogs with hypothyroidism or diabetes Pasteurella multocida types A and D Bovine herpesvirus -1 Ingested toxins activated by p450 enzymes Bordetella bronchiseptica Fusobacterium necrophorum FIP, hepatic abcesses Foreign body in reticulum → penetrates reticular wall and diaphragm → enters pericardial sac → introduces infectious agents Streptococcus equi Strongylus vulgaris, Heartworm, SLE, RMSF, E. rhusiopathiae 1 Excoriation 2 Crust 3 Macule 4 Plaque 5 Wheal 6 Lichenification 7 Papule 8 Nodule 9 Vesicle 10 Bulla 11 Cyst 12 Collarette 13 Scale 14 Pustule 15 Comedo 16 Callus 17 Ulceration 18 Erosion 19 Fissure Raised fluid-filled intra- or sub-epidermal pockets > 1 cm Epithelial lined cavity in dermis/subcutis Deep linear break in the epidermis to the dermis Thickened, firm focus or region of epidermis Raised, flat-topped region ≥1cm in diameter in dermis/epidermis Dried Exudate Raised focus of dermal edema, often with central pallor and erythematous rim Partial loss of epidermis Raised, often solid mass ≥1cm in diameter in dermis/subcutis Layer of scale that expands peripherally Fragmented sheets or corneocytes Shallow linear epidermal clefts Extensive/diffuse epidermal thickening +/- increased pigmentation Raised fluid-filled intra- or sub-epidermal pockets < 1 cm Flat region of skin that has a color change Epidermal pocket of purulent discharge Full loss of Epidermis Follicle distended/plugged by keratin/sebum Raised, firm regions < 1cm in diameter 1 Feline Ulcerative Dermatitis and Stomatitis 2 Dermatophilosis 3 Canine Papillomatosis 4 Contagious Pustular Dermatitis 5 Intertrigo 6 Granulomatous dermatitis/panniculitis 7 Impetigo/Folliculitis 8 Pyotraumatic Dermatitis 9 Cutaneous manifestations of sepsis 10 Greasy Pig Disease Erysipelothrix rhusiopathiae (pigs) Ricketssia rickettsia (dogs) Staphylococcus hyicus FHV-1 Ovine parapoxvirus Mycobacterium Staphylococcus pseudointermedius Skin-fold dermatitis Hot spots CPV-1 Dermatophilus congolensis 1 Feline Cutaneous and Oral Papilloma 2 Demodecosis 3 Dermatophytosis 4 Zygomycosis 5 Facial/Localized Lupus Erythematosus 6 Equine genital papillomas 7 Equine cutaneous papillomas 8 Oomycosis 9 Malassezia dermatitis 10 Equine aural papillomas FcPV-1,2,3 Pythium insidiosum Microsporum and Trichphyton spp. EcPV-2 Conidiobolus sp Self reactive T-cells target keratinocytes → keratinocyte death → erosion to ulceration Malassezia pachydermatis EcPV-1 Demodex canis EcPV-3 1 Vitiligo 2 Type 2 Solar Injury 3 Type 3 Solar Injury 4 Ergotism 5 Streptococcus equi equi / Auto-immune (Strangles) 6 Lick granuloma 7 Type 1 Solar Injury 8 Type 4 Solar Injury 9 Calcinosis Cutis Hyperadrenocorticism Ingestion/administration from plants or drugs with photodynamic pigments Hepatic failure to excrete phylloerythrin from hepatotoxic plants and mycotoxins Idiopathic Moldy feed infected with Claviceps Purpurea produce ergotamine Stress Purpura hemorrhagica Self reactive T-cells target melanocytes → depigmentation, leukotrichia (white hair) Abnormal porphyrin metabolism from congenital porphyria
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