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Cell; cancer pathophysiology

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Cell; cancer pathophysiology

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study for college patho

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Cell; cancer pathophysiology
 

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Cell; cancer pathophysiologyOnline version

study for college patho

by Janitza
1

cell stem

Reserve cells that remain quiescent until there is a need for cell replenishment .
When a divides , one daughter cell retains the stem cell characteristics , and the other daughter cell becomes a progenitor cell that proceeds through to terminal differentiation .
Self - renewal , Potency

2

osteom tumor tumor swelling Tumors Adenoma benign

A is a that can be caused by a number of conditions , including inflammation and trauma .
- are usually named by adding the suffix - oma to the parenchymal tissue type
; benign tumor of glandular epithelial tissue and osteoma ex : of bone tissue =

3

functions genetic destroy Uncoordinated squamous circulatory tissue death Neoplasia malignant autonomous vital metastasize single rapid invade lymphatic secondary slow Carcinoma Hematologic capsules tumors cell surface enters organ MALIGNANT infiltrate detach loose invade standstill proliferation break Metastasis blood adenocarcinoma differentiated ability death benign ischemia spread lymph adenocarcinoma Neoplasms normal solid tissue glandular clustered regress spread Malignant spread Solid invades


that contain well - differentiated cells that are together in mass are considered .
Benign tumors usually do not cause unless their location or size interferes with . Due to unknown reasons these cells have lost the to suppress the program for cell , while still retaining the program for cell differentiation . Slow , progressive rate of growth that may come to a or . Grow by expansion and remain localized to their site of origin , lacking the capacity to , , or to distant sites . Due to expansion , a surrounding rim of compressed connective tissue develop .
Fibrous are compressed connective tissue that is responsible for a sharp line of demarcation between benign tumor and the adjacent tissues which is the factor that facilitates surgical removal .

neoplasms are less well and have the ability to , enter the or system , and form tumors at other sites . Malignant tumors include carcinoma ; malignant tumor and ; malignant tumor .

; used to designate a malignant tumor of glandular epithelial tissue =


­ ; the result from altered cell differentiation and growth process . Means new growth . and relatively . Invade and nearby tissue and widely and have the potential to cause . Due to the growth , the tumors compress blood vessels and outgrow their blood supply , leading to and or injury
TWO TYPES OF NEOPLASMS
tumors ; carcinomas ( epithelial tissue ) and sarcomas ( connective tissue )
cancers ; invade bone marrow and lymphoid tissue

; Initially confined to be a specific or - - > progression of growth . Cells from the original tumor and surrounding tissue - - > the and systems to to distant sites .
; when the detached cells from an original tumor the surrounding tissue and enters the blood and lymph systems to to distant sites



4

kill DNA laser destroy interrupts waves damage particles chemosurgery corrosive process laparoscopic cancer cryosurgery

TYPES OF SURGERY FOR CANCER ; , , surgery , surgery
Cryosurgery ; instilling liquid nitrogen into the tumor through a probe
Chemosurgery ; using a paste with multiple frozen sections to ensure complete removal of the tumor
Laser surgery ; using a laser beam to resect tumor
Laparoscopic surgery ; performing surgery through two small incisions

Radiation treatment ; High energy or / damage cells ; created free radicals which damage cell structures , cell cycle , cells , or in cells

5

weight inappropriate metastatic loss Direct tissue frank paraneoplastic eroded hematopoietic necrosis extension release dermatological Metastatic wasting anemia hemorrhage muscle Seeding cachexia ulceration compressed invasion weakness anorexia cancer neurological seeding

Cancer grows and spread by sending crablike projections into the surrounding tissue

METHODS BY WHICH CANCER SPREADS ; , , and
invasion and
of cancer cells in body cavities
spread through the blood or lymph pathways

CLINICAL MANIFESTATIONS OF CANCER ; integrity , , and syndrome
TISSUE integrity ; blood vessels ; and ; bleeding and

Cancer cachexia ; and of body fat and tissue ; profound , , and

Paraneoplastic syndrome ; hormone , circulating , , and factors

6

hormone embryonic high Aneuploidy procoagulant Intrachromosomal grow synthesis normal Anchorage faulty cell loss Microsatellite antigens Anaplasia loss metastatic rapid secrete proliferate cessation embryonic contact growth clotting anaplastic secretion atypical cell Cell enzymes mitotic bizarre normal telomarse spindles factor instability morphologic degradative absence continue rampantly inhibition embryonic abnormal Cancer

Cancer cells ; Characterized by and proliferation and of differentiation . Undifferentiated cancer cells are marked by a changes . These cells display , figures , sometimes produces .

; term used to describe the of cell differentiation in cancerous tissues . Advanced cancer cells begin to resemble undifferentiated or cells more than they do their tissue origin .

Genetic is considered to be a hallmark of cancer . Characteristics of cancer cells include aneuploidy , intrachromosomal instability , and microsatellite instability .

; chromosomes are lost or gained

instability ; includes insertions , deletions , and amplifications

instability ; involves short , repetitive sequences of DNA ; point mutations

Growth independence refers to cancer cells that have the ability to in the of factors

density - dependent inhibition means the of growth after cells reach certain density . " " . Cancer cells tend to to w / o regard for adjacent tissue .

dependence ; cells must be anchored to live and grow . cells frequently remain viable and multiply w / o attachments to other cells and the EC matrix

Cell - to - communication ; cell to communication
Life span ; divide an infinite number of times . Contain levels of
Antigen expression ; cancer cells revert to patterns of gene expression and produce similar to those found in cells .

Production of substances ; cancer cells may that enable invasion and spread ; also assume or production and of substances that affect mechanisms

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