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Urinary system

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Urinary system

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Urinary System what u need to know.

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Urinary system
 

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Urinary systemOnline version

Urinary System what u need to know.

by Yeslin Santos
1

ECF ions excess pressure production acid body solutes blood environment regulating volume base erythropoietin osmolarity water RBC wastes internal ions D renin vitamin toxins calcitriol blood metabolic fastin Gluconeogenesis regulating

* Removal of , , and from the
* Maintain the ? s :
* Regulate total and ( concentration of ) of the body
* Regulate concentrations of in ( ex . Na + , K + , Ca + , Cl - )
* Maintain - balance
* Hormone production ( for and for )
* Converts to ( its active form )
* during prolonged

2

Ureters Nephrons Urethra Kidneys bladder Urinary

* are major excretory organs
- are the functional excretory units
* is the temporary storage reservoir for urine
* transport urine from the kidneys to the bladder
* transports urine out of the bod y

3

concave Convex Retroperitoneal Ureters nerves blood hilum left lymphatics renal vessels hilu sinus superior lumbar Right

The Kidneys
* , in the region
* kidney is lower than the
* lateral surface , medial surface
* Renal leads to the renal
* , , , and enter and exit at the

4

Minor Medulla Renal Renal Renal Superficial Cortex Column Pelvis calyx Renal

: Contains bulk of nephron structures ; region of kidney

: Containing mostly
collecting ducts

: Runs between each medulla

: Cup shaped , encircles the apex of a pyramid

- Basin area of kidney , continuous with urete r

5

1 long renal Nephrons urine Glomerulus cortex Bowman Renal conserving 85% corpuscle urine capsule Juxtamedullary loops tubule medulla capillaries Nephrons Cortical interface functional concentrated units wate

The Nephron :
Structural and that form
Each kidney contains about million nephrons

Two main parts :
- ( ) : a tuft of
- : begins as cup - shaped glomerular ( ? s ) surrounding the glomerulus


Two Classes
- : About of all nephrons , almost completely in cortex

- : Originate at - , that dip into the medulla ; allow for production of &

6

PCT capillaries Peritubular recta cortical Vasa DCT juxtamedullary

Two Classes
Cortical Nephrons :
associated with and of nephrons

Juxtamedullary Nephrons :
associated with the nephron loop of nephron s

7

walls formation macula tubule signal mechanoreceptors Extraglomerular cells afferent granular NaCl cells densa cells ascending systemic distal cells pressure ascending arteriole blood chemical densa Complex Granular loop arteriole Juxtaglomerular blood JGC convoluted Complex chemoreceptor JGC filtrate nephron afferent Macula arterioles pressure Juxtaglomerular glomerulus communication concentrations Juxtaglomerular Complex JGC renin mesangial

* ( ) : Region where portion of nephron loop lies against the that feeds the

* ( ) : Both the and cells are modified at point of contact

* ( ) helps to regulate rate of &

* ? modified cells of nephron loop ; packed beside granular cells ; cells that monitor of filtrate entering the

* ? found in ; act as , releasing when changes in occur

* ? lie between the nephron loop and arterioles ; allows between and via

8

urine urine pathology blood Nitrogenous high filtered 95% wastes 5% cleansing formation balancing Chemically Abnormally

* water and solutes

* : urea , uric acid , and creatinine

* Other normal solutes
Na + , K + , PO43 ? , and SO42 ? ,
Ca2 + , Mg2 + and HCO3 ?

* concentrations of any constituent may indicate

* and of the blood leads to ? is literally just !

9

filtration Glomerular reabsorption secretion Tubular Tubular

* : " dumping filtrate into the waste container "

* : " reclaiming what the body needs to keep "

* : " selectively adding to the waste container "

10

Colloid filtrate Pressure Filtration osmotic water solutes solutes pressure water inward out formation i Net outward pressure Hydrostatic

* is determined by the differences in and pressures

* of the glomerular capillaries ( HPgc ) aka glomerular BP , promotes , " the push " forcing and of blood

* of the glomerular capillaries ( OPgc ) , " the pull " by blood proteins keeping and

11

pressure acid pain chronic pH bacterial Kidney uric Ca2 infection calcium urine ureter magnesium stones

* form in renal pelvis
- Crystallized , , or salts
* Larger stones block , cause and in kidneys
* May be due to , retention , ? + in blood , ? of urin e

12

Micturition

: Urination or voidin g

13

urethral nervous detrusor ANS urethral sphincter ANS syste sphincter somatic external muscle internal

Three simultaneous events
* Contraction of by
* Opening of by
* Opening of by

14

diet output Urinalysis consistancy urinary 24 1 30 0 Urinalysis metabolism 8 180 urine cellular 150 2

* Blood composition depends on : , and

* In hours , million nephrons of the kidneys filter - liters of blood plasma ; resulting in . - liter of urine output daily
* In healthy individuals , kidneys maintain despite variation in diet and metabolic activity

* allows testing to determine substances present in a urine specimen ? this can be used to assess health of a patient

* must be done within minutes after urine is voide d

15

Transparency gravity Color urine Odor pH Specific of

* and

* ? slightly aromatic

* ranges from 4 . 5 - 8 . 0 ( average of 6 )

* is the relative weight of a specific volume of liquid compared with an equal volume of distilled water . The specific gravity of distilled water is 1 . 000 , because 1 ml weighs 1 gram .

16

water bile pale urochrome UT foods drugs clear Color yellow solutes amber blood Transparency

* and

* Should be and to in color , due to ( pigment metabolite of bilirubin )

* Color variations indicate the relative concentration of to in the urine

* Abnormal urine color may be due to certain , such as beets , various , , or

* Cloudy urine may indicate a

17

pH 5 urine urine 4 infection Diet tract diet whole wheat pH vegetarian 6 odor ammonia urine urine 8 pH disease 0 protein urine of ash drugs acidity urine acid vegetables Bacteria Odor urinary alkalinity increase odor

* ? slightly aromatic
- action gives it an - like
- Some , and various processes alter the characteristic or .
Example : someone with uncontrolled diabetes mellitus makes urine smell fruity or acetone - like .

* ranges from . - . ( average of )
* can influence or
- A diet high in and raise the of . The foods that can
the are called foods .
- A ( alkaline ash diet ) increases the of the .
- A may also result in urine with a high pH .

18

liquid kidney 1 volume ml specific solutes 1 001 stones crystallize gravity 1 more 000 equal hydrometer precipitate urinprober Specific less 1 distilled 030 1 volume water

* is the relative weight of a of compared with an of . The specific gravity of distilled water is . , because weighs gram .

- Measured using a /
- Urine weighs more because it has ? normal is . - . .

- High specific gravity = solutes
Limited fluid intake , fever , kidney inflammation

- Low specific gravity = solutes
Excessive water intake , diabetes insipidus or chronic renal failure

* If urine becomes excessively concentrated , some substances normally held in solution begin to or forming ( renal calculi ) .

19

tubules ducts cell Hyaline cell blood blood red white pathological convoluted Hardened distal collecting Casts

:
* cell fragments , formed in &
* , and casts
* Always indicate a conditio n

20

active blood High mechanisms Glucosuria carbohydrate transport mellitus levels inadequate Glucose exceeded sugar insulin diabetes Glycosuri

( ) :
* due to levels ; or can result when for glucose are temporarily
* Excessive intake
* Uncontrolled
* Aka

21

Toxins Hypertension Pathological kidney intake overabundant glomerulus permeability big pregnancy Poisons Albumin exertion excessive protein increased trauma

* - albumin in urine

- Normally albumin is too to pass through the ? so when it does you have an abnormally of the membrane .

- Nonpathological conditions :
, ,

- conditions usually events that damage the glomerular membrane
*
*
*
*

22

acidosis larger diets starvation fat glucose bodies beta carbohydrates mellitu acetone abnormal diabetes ketones acid acid ketone small metabolic hydroxybutyric

* Ketone Bodies ( Ketonuria ) :
Acetoacetic , - and are .

- Normally found in amounts in urine

- If amounts usually indicates processes are occurring . The result is .

- Expect to see this during or very low in ? inadequate food forces the body to use its stored .

- Finding both and usually indicates

23

Blood big pathology Cells rbc Red

* ( hematuria ) :
Indicates of the urinary tract ? are too to pass through glomerular pores

- Kidney stones
- Infection
- Tumors
- Physical trauma to urinary organ s

24

RBCs Hemoglobin hemolysis

* ( Hemoglobinuria ) in urine as a result of ( bursting ) of

* Indicates
- Hemolytic anemias
- Transfusion reactions
- Burns
- Venomous snake bites
- Renal diseas e

25

bladder urine inflammation liver Cells Blood Bile Nitrites infection shaken yellow foam bacterial infection White trac Pigments pathology urinary

*
- May indicate a ( E . coli )
- Valuable for early indicators of

* ( Bilirubinuria ) bilirubin in urine ( bile pigments )
Usually indicates
- hepatitis
- cirrhosis
- bile duct blockage
Usually forms when urine is

* ( Pyuria ) presence of white blood cells in ( pus )
- Indicates of

26

Diabetes Pyelonephritis Glomerulonephritis mellitus Diabetes insipidus Gonorrhea

* - kidney infection

* - " glomerular disease " acute inflammation of the kidney , typically caused by an immune response

* - sexually transmitted bacterial infection

* - diabetes - too much sugar in the blood

* - rare - caused by a deficiency of the pituitary hormone ADH ( vasopressin ) which regulates kidney function .

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