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HEMOSTASIA

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HEMOSTASIA

Created by

Wendy Ibañez
Wendy Ibañez
Bolivia

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HEMOSTASIA
 

HEMOSTASIAOnline version

HEMOSTASIA

by Wendy Ibañez
1

Pruebas de laboratorio: TP (Tiempo de Protrombina): vía extrínseca, TTPa (Tiempo parcial de tromboplastina activado): vía intrínseca. PLAQUETAS

2

La vía intrínseca se activa por contacto con superficies negativas; incluye factores XII, XI, IX y VIII.

3

El TP (tiempo de protrombina) evalúa la vía extrínseca, mientras que el TTPa (tiempo parcial de tromboplastina activado) evalúa la intrínseca.

4

La proteína C activada, junto a la proteína S, inactiva los factores Va y VIIIa, limitando la generación de trombina.

5

El plasminógeno se activa a plasmina por acción del t-PA (activador tisular del plasminógeno). La plasmina degrada la fibrina del coágulo.

6

Tenemos 14 factores de coagulación

7

Todos los factores de la coagulación se sintetizan en el hígado, el corazón y el riños

8

La Hemofilia se caracteriza por sangrado cutáneo mucoso y déficit de factor 7 y 8 principalmente

9

Sangrado en sepsis con elevación de dímero D Diagnóstico probable: coagulación intravascular diseminada (CID).

10

En los pacientes cirróticos tienes disminuidos los niveles de todos los factores pero además también el recuento de plaquetas

11

Fibrinógeno en la hemostasia Es el precursor de la fibrina, clave en la formación del coágulo estable

12

¿que es el Dímero D? prueba que evalúa consumo de plaquetas y muy útil en sepsis

 
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