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Physiological / Endocrinological Basis of Contraception

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Physiological / Endocrinological Basis of Contraception

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Contraception

Created by

Precious
Precious
United Kingdom

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Physiological / Endocrinological Basis of Contraception
 

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Physiological / Endocrinological Basis of ContraceptionOnline version

Contraception

by Precious
1

Combined Oral Contraceptive Pill ( COCP )
Composition : Synthetic and .
Types :
: Same hormone dose every active pill .
: Varying hormone doses to mimic natural cycle hormone fluctuations .
Mechanism ( Monophasic ) :
Taken for days , suppressing and from the .
Mimics the mid - / phase , when steady levels prevent .
Hormone levels are than what would be triggered by the , so the endometrium stays ? bleeding .
Last days are placebo or suspended pills ? hormone levels dramatically , causing withdrawal bleeding ( not true menstruation ) .
Continuous use can the menstrual cycle .
Mechanisms ( Multiphasic ) :
Hormone levels to mimic the natural cycle .
Use synthetic hormone overall than monophasic pills .
Considerations :
Oestrogen affects the ? increases factors ? risk of cardiovascular events and blood clots , for example in .

2

Progesterone - Only Pill ( POP / Mini Pill )
Composition : Low - dose progesterone ( higher in injections / IUDs ) .
Mechanism :
Primarily suppresses , but can occasionally surge ? may still occur .
Thickens cervical mucus ? harder for sperm to pass .
Keeps endometrium , preventing , but does not reliably prevent .
Irregular may still occur due to occasional ovulation .
Key points :
Timing is critical to maintain steady progesterone levels ( same time every day ) .
Consistency keeps cervical mucus thick .

3


Hormonal Intrauterine Device ( IUD )
Releases synthetic progesterone locally .
Mechanism similar to POP but more effective due to local delivery .
Duration : ? 8 years .
Copper Intrauterine Device ( IUD )
Releases toxic to sperm ( non - hormonal ) .
Progesterone Implants and Injections
Implants : Last years .
Injections : Last weeks .

 
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