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BIO LT PART 1

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BIO LT PART 1

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Module 1

Created by

John Magsalin
John Magsalin
Philippines

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BIO LT PART 1
 

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BIO LT PART 1Online version

Module 1

by John Magsalin
1

Therapeutics use transformations to create products . A is combined with a microbial to form a .

2

Wilhelm Johansenn coined the terms :

- The basic physical and functional unit of heredity , made up of a specific sequence of DNA

- The observable characteristics that result from the interaction of genotype and environment .

- An organism's complete genetic makeup .

3

Oswald , Colin , and Maclyn suggested that could be the holder of information .

They built off from observation that dead but cells ( S - strain ) can still find a way to overtake still - alive but member ( R - cells ) of the same family . When the R - cells absorbed some of the S - strain material , they turned into S - strain themselves . He called this process the principle .

He did not know what was being transferred , however , and just knew that something was being .

4

Oswald , Colin , and Maclyn then recreated the experiment .

They had three tubes of dead S - cells and alive R - cells together . Based on 's work , the R - cells would absorb something from the S - cells to become S - cells themselves . They just had to identify what .

This time , they added a specific mixture to kill certain elements that were candidates for the holder of material .

They added , , and . These kill DNA , RNA , and Protein respectively .

5

Oswald Avery , Colin Macleod , and Maclyn Maccarty's idea was that if X element was being transferred between the two cells and they added Xase - a substance that kills the element X , then the R - cells could no longer be S - cells .

( for example , if we use the protein killer and protein has the genetic material , then the S - cells could no longer transfer their data to the - cells so that they can become - cells . )

It turns out , only the sample did not turn into S - cells .

Meaning , if you add the DNA killer DNase , the S - cells could no longer transfer their to the R - cells .

This meant the contained genetic material !

6

James and Francis explained that DNA has a helix structure

7

Rosalind and Maurice confirmed the double helix structure . Through X - Ray

was able to identify the two types of DNA : A DNA and B DN A

8

Alfred and Martha in determined that is the holder of material .

They marked proteins and DNA with in bacteriophages .

Bacteriophages spread copies of themselves in other cells , baby versions of themselves .

Hershey and Chase wanted to see if the mini duplicating bacteriophages uses DNA or protein to replicate themselves .

They found that they marked with radiation , the cells had radiation too . On the other hand , when they marked with radiation , the cells did not have radiation .

 
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