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Froggy Jumps
Froggy Jumps

ETAPA 2: Ensayos Preclínicos

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ETAPA 2: Ensayos Preclínicos

Froggy Jumps

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About this activity

Repasa conceptos clave de farmacocinética y farmacodinámica.

Created by

Joel Santas
Joel Santas
Mexico

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ETAPA 2: Ensayos Preclínicos
 

Froggy Jumps

ETAPA 2: Ensayos PreclínicosOnline version

Repasa conceptos clave de farmacocinética y farmacodinámica.

by Joel Santas
1

¿Qué mide Cmax en un estudio farmacocinético?

2

¿Qué ensayo evalúa unión al receptor diana in vitro?

3

¿Qué significa NOAEL?

4

¿Qué es HED en toxicología?

5

¿Qué mide AUC en farmacocinética?

6

¿Qué fase clínica evalúa seguridad en humanos?

7

¿Qué modelo se usa para estudiar metabolismo hepatic?

8

¿Qué mide la vida media en PK?

9

¿Qué prueba se usa para dolor en animales?

10

¿Qué objetivo tiene la Fase 2 en ensayos clínicos?

11

En estudios de farmacocinética, ¿qué parámetros se miden para entender la exposición de un fármaco?

12

¿Qué ensayo in vitro se usa para estudiar absorción en intestino?

13

Para estudiar distribución con marcadores, ¿qué se usa?

14

¿Qué prueba define toxicidad aguda de un fármaco?

15

¿Qué es NOAEL?

16

¿Qué cálculo convierte dosis animal a humano (HED)?

17

¿Qué fase clínica verifica seguridad y ADME en humanos?

18

En Fase 2, ¿cuántos participantes están típicamente?

19

¿Qué mide la Fase 1 además de seguridad?

20

¿Cuál es el objetivo de la Fase 4 (postcomercialización)?

 
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