Matching Pairs GI drug Matching!!Online version Match the drug to its class, MOA, adverse effect and more by Tamia Witherspoon 1 Methylnaltrexone bromide 2 Metoclopramide 3 Docusate 4 Alosetron 5 Senna 6 Omeprazole 7 cimetidine 8 Psyllium 9 Pancrelipase 10 Loperamide 11 Misoprostol 12 Sucralfate 13 Magnesium citrate 14 Sodium bicarbonate Osmotic Laxatives Bulk-Forming Laxatives Chemical stimulants laxatives GI Stimulants Opioid Antagonist Protein pump inhibitors histamine-2 antagonist Lubricants Drug used to treat digestive enzyme dysfunction Gastrointestinal protect IBS and Chronic Constipation drugs Antacids Antidiarrheal Prostaglandin 1 Misoprostol 2 Pancrelipase 3 Omeprazole 4 Alosetron 5 Magnesium citrate 6 Cimetidine 7 Methylnaltrexone bromide 8 Senna 9 Loperamide 10 Metoclopramide 11 Sucralfate 12 Psyllium 13 Sodium bicarbonate 14 Docusate Forms a thick paste w/ stomach acid that adheres to ulcers Accelerates gastric emptying Inhibits peristalsis & prolongs transit time. Lowers gastric acid secretion Neutralizes stomach acid Rises firmness in stool & lowers urgency Draws water into intestine, promotes peristalsis Facilities the digestion of fat, carbohydrates, and protein in the GI tract Draws water into stool, resulting in softer stool Blocking opioid receptors in the GI tract w/out affecting pain relief in the brain. Restores normal bowel movement & secretion. Stimulates peristalsis Lowers stomach acid secretion, raises production of protective mucus & bicarbonate = causes uterine contractions Combines w/ water in intestines to soften stool & increase bulk Blocks H2 receptors in the stomach, reducing gastric acid secretion 1 Senna 2 Cimetidine 3 Pancrelipase 4 Docusate 5 Misoprostol 6 Omeprazole 7 Metoclopramide 8 Sodium bicarbonate 9 Sucralfate 10 Psyllium 11 Magnesium citrate 12 Alosetron 13 Loperamide 14 Methylnaltrexone bromide Toxic megacolon (rare but serious), Dysmenorrhea (painful & severe menstrual cramps), irregular periods (hypermenorrhea), miscarriage Diarrhea, Nausea, Abdominal pain Rigidity, tremors, restlessness. Tardive dyskinesia, seizures, Parkinson’s-like symptoms, low BP & HR ( due to parasympathetic stimulation) Constipation, Vertigo, Insomnia, Indigestion Mild cramping, Frequent use can interfere w/ the absorption of fat-soluble vitamins A, D, E, & K long term use=deficiency. C.diff, bone fractures, magnesium, calcium, B12 deficiency Cardiac arrest, Gynecomatia, Somnolence Constipation, Diarrhea, Fluid retention, Electrolyte issues Mild cramping, nausea, vomiting. Severe abdominal pain or diarrhea➡️may indicate GI perforation or need for dose reduction/discontinuation Hyper magnesium, cramping, bloating, diarrhea. Constipation, ischemic colitis Cathartic dependence 1 Sucralfate 2 Psyllium 3 Magnesium citrate 4 Loperamide 5 Pancrelipase 6 Prostaglandin 7 Docusate 8 Omeprazole 9 Metoclopramide 10 Alosetron 11 Sodium bicarbonate 12 Methylnaltrexone bromide 13 Senna 14 Cimetidine Duodenal & gastric ulcers, GERD Zollinger-Ellison Prevention of gastric ulcers in pts taking NSAIDs. Also induces labor by ripening the cervix. Duodenal ulcers Relieve different levels of diarrhea (acute, chronic, irritable bowel syndrome (IBS), reducing ileostomy discharge Peptic ulcer disease, GERD Constipation, prevention of straining, and management of chronic watery diarrhea. Chronic noncancer pain Gastroparesis, Nausea, vomiting GERD. Constipation, bowel prep before a surgery or procedure. Short term treatment of constipation. Bowel prep before surgery or procedure. Draws water into stool, resulting in softer stool. Duodenal & gastric ulcers, GERD, Zollinger-Ellison syndrome IBS w/ diarrhea Pancreatic insufficiency related to pancreatitis, cystic fibrosis, GI bypass surgery. 1 Sodium Bicarbonate 2 Omeprazole 3 Loperamide 4 Cimetidine 5 Psyllium 6 Pancrelipase 7 Docusate 8 Senna 9 Alosetron 10 Methylnaltrexone bromide 11 Magnesium citrate 12 Sucralfate 13 Metoclopromide Take immediately before or w/ meals & snacks, swallow whole!, if pill is difficult to swallow open pill & sprinkle on acidic food. Swallow whole!, report diarrhea, abdominal pain, and bloody stools. Take before meals preferably in the morning. Try using only for short-term Take w/ a full glass of water, increase fiber, fluid, & exercise, don’t take before bedtime, report persistent constipation or abdominal pain. Report unusual facial or body movements, restlessness, or muscle stiffness immediately. Report severe abdominal pain, nausea, or diarrhea. Hydration & diet changes to promote natural bowel motility. Increase fluids, fiber, & activity. Don’t use daily to avoid dependence, report severe abdominal pain or persistent constipation. Take w/ a full glass of water, increase fiber & fluid intake, short term use only, results may take several days. Don’t Double up, report black/tarry stools, avoid caffeine, and take before meals or at bedtime Symptom managing, not a cure, hydration and dietary fiber as tolerated Always follow label directions carefully, report prolonged diarrhea or cramping, short term relief only, raise adequate fluid intake. Take after meals & at bedtime, 1-2 hrs. before or after other medications. Fluid & electrolyte replacement during diarrhea episodes. Avoid bismuth in children or teens w/ viral infections. Take 1 hr before meals & at bedtime (4 times a day), increase fluid & fiber intake, swallow whole!
NURSE NERD NERVES STUFF