Immunodeficiency disorders Essentials Quiz

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Test your immunology basics with key disorders.

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Quader Ahmed Jalili

India

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Immunodeficiency disorders Essentials Quiz


Froggy Jumps Immunodeficiency disorders Essentials QuizOnline version Test your immunology basics with key disorders. by Quader Ahmed Jalili 1 Which defect causes Chronic Granulomatous Disease (CGD)? a Complement C3 deficiency b NADPH oxidase deficiency c Myeloperoxidase excess 2 Bruton disease primarily affects which cells? a Neutrophils b B cells c T cells 3 DiGeorge syndrome results from defective development of which organ? a Spleen b Lymph nodes c Thymus 4 Wiskott–Aldrich syndrome is X-linked and involves? a Isolated IgA deficiency b Thrombocytopenia with eczema c Hyperpigmentation and anemia 5 Isolated IgA deficiency mainly affects? a Systemic IgG levels b Mucosal immunity c T cell receptor rearrangement 6 Hyper-IgM syndrome features which isotype profile? a All immunoglobulins elevated b High or normal IgM with low others c Low IgM and high IgG 7 SCID typically presents with failure of? a Neutrophil degranulation b Only NK cell responses c T and B cell responses 8 Purine Nucleoside Phosphorylase (PNP) deficiency predominantly affects which lineage? a B cells b T cells c Megakaryocytes 9 Leukocyte Adhesion Deficiency (LAD) is due to defect in? a β2 integrin (CD18) b C3 convertase c CD3 10 Chronic mucocutaneous candidiasis indicates a defect in? a Humoral immunity only b Cell-mediated immunity c Complement system 11 Chediak–Higashi syndrome includes defects in? a B cell receptor signaling b Phagosome-lysosome fusion c T cell receptor expression 12 CGD catalyzes killing of bacteria via what mechanism? a Antibody opsonization b Complement activation c Reactive oxygen species by NADPH oxidase 13 What is a hallmark of Ataxia Telangiectasia? a Hyper IgA syndrome b Cerebellar ataxia and telangiectasia c Neutropenia and purpura 14 Job’s Syndrome is also known as? a DiGeorge syndrome b Wiskott–Aldrich syndrome c Hyper-IgE syndrome 15 Common Variable Immunodeficiency primarily shows? a Normal immunoglobulins with infections b Hypogammaglobulinemia c Hypergammaglobulinemia 16 Secondary immunodeficiencies can be caused by which? a Purely genetic mutations b HIV infection c Vaccinations 17 Which is a primary T cell defect disorder? a Isolated IgA deficiency b DiGeorge syndrome c Common variable immunodeficiency 18 Common cause of recurrent pyogenic infections due to B cell defects? a Bruton disease b Griscelli syndrome c CGD 19 Treatment often successful for many primary immunodeficiencies is? a Antibiotics only b Vaccination only c Bone marrow transplantation

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Immunodeficiency disorders Essentials Quiz

Froggy Jumps

About this activity

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Immunodeficiency disorders Essentials QuizOnline version

by Quader Ahmed Jalili

Which defect causes Chronic Granulomatous Disease (CGD)?

Bruton disease primarily affects which cells?

DiGeorge syndrome results from defective development of which organ?

Wiskott–Aldrich syndrome is X-linked and involves?

Isolated IgA deficiency mainly affects?

Hyper-IgM syndrome features which isotype profile?

SCID typically presents with failure of?

Purine Nucleoside Phosphorylase (PNP) deficiency predominantly affects which lineage?

Leukocyte Adhesion Deficiency (LAD) is due to defect in?

Chronic mucocutaneous candidiasis indicates a defect in?

Chediak–Higashi syndrome includes defects in?

CGD catalyzes killing of bacteria via what mechanism?

What is a hallmark of Ataxia Telangiectasia?

Job’s Syndrome is also known as?

Common Variable Immunodeficiency primarily shows?

Secondary immunodeficiencies can be caused by which?

Which is a primary T cell defect disorder?

Common cause of recurrent pyogenic infections due to B cell defects?

Treatment often successful for many primary immunodeficiencies is?