Systemic candidiasis & Mycoses Diseases Quiz

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Test your knowledge of systemic candidiasis and systemic mycoses.

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Quader Ahmed Jalili

India

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Systemic candidiasis & Mycoses Diseases Quiz


Froggy Jumps Systemic candidiasis & Mycoses Diseases QuizOnline version Test your knowledge of systemic candidiasis and systemic mycoses. by Quader Ahmed Jalili 1 Which organism causes histoplasmosis? a Blastomyces dermatitidis b Histoplasma capsulatum c Coccidioides immitis 2 Histoplasma capsulatum is typically found in which soil? a Dry desert soil b Saline coastal sand c Humid, acidic soil with bird or bat droppings 3 What is the common name for histoplasmosis? a Darling’s disease b Candidiasis c Valley fever 4 Disseminated histoplasmosis occurs mainly in which patients? a Those with low immunity (e.g., HIV/AIDS) b Children under 5 c Young healthy adults 5 Which diagnostic specimen is commonly used for histoplasmosis? a Cerebrospinal fluid b Sputum or bone marrow aspirate c Synovial fluid 6 Which form is seen in Histoplasma capsulatum staining? a Broad-based yeast b Oval yeast cells 2–4 μm c Gram-positive bacilli 7 What is the drug of choice for histoplasmosis? a Liposomal amphotericin B b Fluconazole c Itraconazole 8 Blastomycosis is primarily caused by which organism? a Coccidioides immitis b Blastomyces dermatitidis c Histoplasma capsulatum 9 Which feature is characteristic of Blastomyces dermatitidis on histology? a Narrow-necked budding b Broad-based budding yeast c Intracellular yeasts only 10 Blastomycosis commonly presents with which site involvement? a Only CNS involvement b Only skin lesions c Lungs with possible skin bone or CNS spread 11 Paracoccidioidomycosis is endemic to which region? a South American countries b North America c Europe 12 Paracoccidioides brasiliensis forms what yeast arrangement? a Mickey mouse/pilot wheel buds b Bartonella-like rods c Broad-based budding only 13 Drug of choice for paracoccidioidomycosis? a Fluconazole b Amphotericin B c Itraconazole 14 Coccidioidomycosis is also known as what? a Valley fever b San Joaquin fever c Rose gardener’s disease 15 Coccidioides infections form what structure in tissue? a Yeast oasis b Spherules filled with endospores c Germ tube colonies 16 Which drug is commonly used to treat coccidioidomycosis? a Itraconazole b Terbinafine c Fluconazole only 17 Which organism causes candidiasis? a Aspergillus fumigatus b Candida species c Histoplasma capsulatum 18 What is a key virulence factor in Candida species? a Pseudohyphae and phospholipase b Endotoxin production c Capsule formation 19 Which test is positive for Candida albicans identification? a India ink b Germ tube test c Capsule staining 20 Which culture medium shows light-green colonies for C. albicans? a CHROMagar b Sabouraud dextrose agar c Blood agar 21 Which organism is emerging and multidrug resistant in healthcare settings? a Candida auris b Candida krusei c Candida parapsilosis 22 Which method indicates invasive fungal infection via a circulating marker? a Procalcitonin b CRP c Beta-D-glucan assay 23 Which predisposing factors raise risk for candidiasis? a Immunosuppression and hospitalization b Young age only c Outdoor exposure only 24 Candidiasis can present as which forms? a Only systemic b Invasive, mucosal, cutaneous, allergic c Only mucosal 25 Which organism commonly causes vulvovaginal candidiasis? a Candida species b Aspergillus c Cryptococcus 26 Which laboratory finding supports Candida infection? a Gram-positive oval budding yeast with pseudohyphae b Gram-negative rods c Acid-fast bacilli 27 Which antifungals are used for systemic candidiasis? a Nystatin only b Griseofulvin c Fluconazole or caspofungin or amphotericin B 28 Candida glabrata is notable for what trait? a Dermal toxin b Nosocomial candidiasis risk c Capsule production 29 Which test helps identify Candida species beyond germ tube? a Acid-fast stain b Molecular methods (PCR) c Gram stain only 30 Which symptom is common in pulmonary histoplasmosis? a Severe wheeze only b Flu-like illness c Acute kidney injury 31 What is the classic Histoplasma appearance on Giemsa stain? a Tiny oval yeasts 2–4 μm b Encapsulated bacilli c Broad-based budding yeasts 32 What is the canine-like mnemonic for dimorphic fungi listed? a Dimorphic Fungi Mnemonic b Yeast to mold switch c Body Heat Probably Changes ShaPe 33 Dimorphic fungi exist as what forms inside and outside the body? a Yeast at 37°C; mold at 25°C b Mold at all temperatures c Yeast at all temperatures 34 Which diseases are included under systemic mycoses? a Only candidiasis b Histoplasmosis, Blastomycosis, Coccidioidomycosis, Paracoccidioidomycosis c Only histoplasmosis 35 What is the hallmark of coccidioidomycosis lab diagnosis? a Spherules with endospores b Giemsa-stained yeasts c Capsule staining 36 Which organism is linked to the Ohio River valley region? a Histoplasma capsulatum b Paracoccidioides brasiliensis c Coccidioides immitis 37 Which form characterizes candidiasis infections? a Viral co-infection b Localized only c Hematogenous spread causing invasive disease 38 Which test helps differentiate Candida albicans from others? a India ink b Capsule stain c Germ tube test is positive for C. albicans 39 What is a common source for Histoplasma exposure? a Fresh water exposure b Insects c Bird or bat droppings 40 Which fungus shows a pilot wheel yeast arrangement? a Histoplasma b Paracoccidioides brasiliensis c Blastomyces 41 Which antigen test indicates fungal infection, not species-specific? a Mannan only b Beta-D-glucan c Galactomannan 42 Which species causes mucocutaneous candidiasis commonly? a Candida species b Aspergillus fumigatus c Cryptococcus neoformans 43 In candidiasis, which specimen can be colonized without treatment? a CSF only b Urine or sputum c Blood only 44 Which imaging or culture result supports Blastomyces diagnosis? a Acid-fast bacilli b Yeast with broad-based budding; culture on SDA c Gram-positive diplococci 45 Which condition is described as Valley fever? a Histoplasmosis b Coccidioidomycosis c Paracoccidioidomycosis 46 Which agent is used for treatment of many systemic mycoses? a Liposomal amphotericin B b Chloroquine c Azithromycin 47 Which organism causes Candida auris outbreaks? a Candida albicans b Candida parapsilosis c Candida auris 48 Which test shows 5 mm induration indicating past infection? a CHROMagar b Coccidioides skin test (coccidioidin or spherulin) c Germ tube test 49 Which fungus is dimorphic and causes systemic illness worldwide? a Aspergillus fumigatus b Candida albicans c Histoplasma capsulatum 50 What form does Coccidioides produce in tissue? a Spherules with endospores b Budding yeast c Pseudohyphae 51 Laboratory diagnosis for candidiasis includes which culture result? a Purple colonies on MacConkey b Creamy white, pasty colonies on SDA c Non-growth on SDA 52 Which organism shows germ tube positivity? a Candida glabrata b Candida albicans c Candida krusei 53 Which agent is linked with 'pilot wheel' appearance? a Histoplasma capsulatum b Paracoccidioides brasiliensis c Coccidioides immitis 54 A key diagnostic marker for invasive fungal infection is? a β-d-Glucan assay b Procalcitonin c CRP 55 Which disease can present with oral lesions and mucocutaneous involvement? a Paracoccidioidomycosis b Coccidioidomycosis c Histoplasmosis 56 Which species is commonly tested via CHROMagar color? a Histoplasma b Blastomyces c Candida species 57 What is a common route of transmission for many systemic mycoses? a Inhalation of spores b Ingestion of contaminated water c Direct contact with skin 58 Which condition is also called desert rheumatism? a Blastomycosis b Histoplasmosis c Coccidioidomycosis 59 Which organism can cause endophthalmitis in invasive disease? a Candida b Cryptococcus c Aspergillus 60 What form do Histoplasma yeasts take inside macrophages? a Capsulated yeasts b Free-floating yeast in blood c Intracellular yeast in phagolysosome 61 Which disease has a drug of choice of liposomal amphotericin B in severe cases? a Cryptococcosis b Histoplasmosis c Candidiasis 62 Which organism is linked to occupational exposure in caves? a Coccidioides immitis b Histoplasma capsulatum c Paracoccidioides brasiliensis 63 What is the typical presentation of acute pulmonary blastomycosis? a Acute pneumonia-like illness b Renal failure c Asymptomatic only 64 Which test can differentiate C. albicans from other species? a Germ tube test b India ink c KOH prep 65 Which of the following is NOT a systemic mycosis? a Histoplasmosis b Coccidioidomycosis c Aspergillosis 66 Which of these is a common predisposing factor for systemic candidiasis? a Hospitalization and invasive devices b Vaccination c Outdoor camping 67 Which organism can form mycelial and yeast forms at different temperatures? a Only molds b Dimorphic fungi (e.g., Histoplasma, Blastomyces, Coccidioides, Paracoccidioides) c Only yeasts 68 Which disease is known as Darling’s disease? a Blastomycosis b Paracoccidioidomycosis c Histoplasmosis 69 Which clinical manifestation is typical for disseminated histoplasmosis? a Skin rashes only b Bone marrow and spleen involvement c Peripheral neuropathy 70 Which organism is associated with a 120-kDa BAD-1 virulence factor? a Blastomyces dermatitidis b Histoplasma capsulatum c Coccidioides immitis 71 Which species is commonly tested with DH test and chlamydospore production? a Candida krusei b Candida glabrata c Candida albicans 72 Which disease shows spherules in tissue biopsy? a Histoplasmosis b Coccidioidomycosis c Paracoccidioidomycosis 73 Which treatment is sometimes used for severe coccidioidomycosis? a Griseofulvin b Itraconazole c Nystatin 74 Which organism causes mucocutaneous candidiasis? a Candida dubliniensis b Candida species c Candida krusei 75 Which diagnostic culture yields yeast form at 37°C for dimorphic fungi? a MacConkey agar only b Culture on SDA with appropriate conditions c Blood agar only 76 Which disease has a wing-like broad-based budding described as Mickey mouse appearance? a Blastomycosis b Histoplasmosis c Paracoccidioidomycosis 77 Which genus is associated with “pilot wheel” yeast forms? a Paracoccidioides b Histoplasma c Coccidioides 78 Which diagnostic method is used for coccidioidomycosis serology? a Immunodiffusion and complement fixation (CFT) b Gram stain c Acid-fast stain 79 Which condition is treated with amphotericin B as a first-line option? a Nocardiosis b Dermatophytosis c Histoplasmosis (severe cases) 80 Which organism is responsible for North American blastomycosis? a Paracoccidioides brasiliensis b Histoplasma capsulatum c Blastomyces dermatitidis 81 Which organism is primarily inhaled to cause paracoccidioidomycosis? a Spores b Bacterial spores c Protozoa 82 Which test detects antibodies for coccidioidomycosis? a Acid-fast stain b Immunodiffusion c Gram stain 83 Which disease presents with endospores inside spherules? a Histoplasmosis b Blastomycosis c Coccidioidomycosis 84 Which genus produces chlamydospores detectable in culture? a Aspergillus b Candida c Cryptoocc 85 Which disease is primarily diagnosed by culture showing mycelial and yeast forms? a Coccidioidomycosis b Candidiasis c Histoplasmosis 86 Which organ is commonly affected in disseminated histoplasmosis? a Skin only b Bone marrow c Kidney only 87 Which feature aids in differentiating Coccidioides from others in culture? a Germ tubes b Capsules c Arthroconidia in hyphae 88 Which disease is associated with pneumonia-like symptoms after inhalation of arthroconidia? a Histoplasmosis b Candidiasis c Coccidioidomycosis

Systemic candidiasis & Mycoses Diseases Quiz

Froggy Jumps

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Systemic candidiasis & Mycoses Diseases QuizOnline version

by Quader Ahmed Jalili

Which organism causes histoplasmosis?

Histoplasma capsulatum is typically found in which soil?

What is the common name for histoplasmosis?

Disseminated histoplasmosis occurs mainly in which patients?

Which diagnostic specimen is commonly used for histoplasmosis?

Which form is seen in Histoplasma capsulatum staining?

What is the drug of choice for histoplasmosis?

Blastomycosis is primarily caused by which organism?

Which feature is characteristic of Blastomyces dermatitidis on histology?

Blastomycosis commonly presents with which site involvement?

Paracoccidioidomycosis is endemic to which region?

Paracoccidioides brasiliensis forms what yeast arrangement?

Drug of choice for paracoccidioidomycosis?

Coccidioidomycosis is also known as what?

Coccidioides infections form what structure in tissue?

Which drug is commonly used to treat coccidioidomycosis?

Which organism causes candidiasis?

What is a key virulence factor in Candida species?

Which test is positive for Candida albicans identification?

Which culture medium shows light-green colonies for C. albicans?

Which organism is emerging and multidrug resistant in healthcare settings?

Which method indicates invasive fungal infection via a circulating marker?

Which predisposing factors raise risk for candidiasis?

Candidiasis can present as which forms?

Which organism commonly causes vulvovaginal candidiasis?

Which laboratory finding supports Candida infection?

Which antifungals are used for systemic candidiasis?

Candida glabrata is notable for what trait?

Which test helps identify Candida species beyond germ tube?

Which symptom is common in pulmonary histoplasmosis?

What is the classic Histoplasma appearance on Giemsa stain?

What is the canine-like mnemonic for dimorphic fungi listed?

Dimorphic fungi exist as what forms inside and outside the body?

Which diseases are included under systemic mycoses?

What is the hallmark of coccidioidomycosis lab diagnosis?

Which organism is linked to the Ohio River valley region?

Which form characterizes candidiasis infections?

Which test helps differentiate Candida albicans from others?

What is a common source for Histoplasma exposure?

Which fungus shows a pilot wheel yeast arrangement?

Which antigen test indicates fungal infection, not species-specific?

Which species causes mucocutaneous candidiasis commonly?

In candidiasis, which specimen can be colonized without treatment?

Which imaging or culture result supports Blastomyces diagnosis?

Which condition is described as Valley fever?

Which agent is used for treatment of many systemic mycoses?

Which organism causes Candida auris outbreaks?

Which test shows 5 mm induration indicating past infection?

Which fungus is dimorphic and causes systemic illness worldwide?

What form does Coccidioides produce in tissue?

Laboratory diagnosis for candidiasis includes which culture result?

Which organism shows germ tube positivity?

Which agent is linked with 'pilot wheel' appearance?

A key diagnostic marker for invasive fungal infection is?

Which disease can present with oral lesions and mucocutaneous involvement?

Which species is commonly tested via CHROMagar color?

What is a common route of transmission for many systemic mycoses?

Which condition is also called desert rheumatism?

Which organism can cause endophthalmitis in invasive disease?

What form do Histoplasma yeasts take inside macrophages?

Which disease has a drug of choice of liposomal amphotericin B in severe cases?