Gene Therapy Primer Quiz

Froggy Jumps

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About this activity

Test your gene therapy basics.

Created by

Carolina Arias

Mexico

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Froggy Jumps Gene Therapy Primer QuizOnline version Test your gene therapy basics. by Carolina Arias 1 What is somatic gene therapy? a Germ cells are edited to be heritable. b Therapeutic genes are added to non-reproductive cells in the patient. c Genes are edited in sperm or eggs only. 2 What distinguishes germline therapy from somatic therapy? a Germline edits are not heritable. b Germline edits can be passed to future generations. c Germline edits only affect bacteria. 3 What is a common delivery method in gene therapy? a Viral or non-viral vectors deliver the gene. b Direct protein infusion only. c DNA editing occurs without any carrier. 4 What does ex vivo gene therapy involve? a Inserting genes directly into the patient’s brain. b Modifying cells outside the body and reinfusing them. c Only editing germ cells. 5 Which disease areas are targeted by gene therapy? a Neurological disorders, cancer, inherited diseases, infections. b Only metabolic disorders. c Only cosmetic conditions. 6 What is ProSavin related to? a A gene therapy strategy to restore dopamine in Parkinson’s disease. b A vaccine for malaria. c A CRISPR editing tool. 7 What is a major ethical concern with germline therapy? a Potential heritable genetic changes across generations. b It only affects plants. c No safety concerns exist. 8 What role do promoters play in transgenesis? a They control when and where a gene is expressed. b They delete genes. c They encode therapeutic proteins only. 9 What is a conditional knockout? a A permanent global gene addition. b Gene deletion that occurs in specific tissues or times. c An unrelated protein tagging method. 10 Which statement is true about gene therapy vectors? a They act as vaccines without delivering genes. b They only edit DNA in test tubes. c They carry the therapeutic gene into target cells.

Froggy Jumps

Gene Therapy Primer QuizOnline version

Test your gene therapy basics.

by Carolina Arias

What is somatic gene therapy?

Germ cells are edited to be heritable.

Therapeutic genes are added to non-reproductive cells in the patient.

Genes are edited in sperm or eggs only.

What distinguishes germline therapy from somatic therapy?

Germline edits are not heritable.

Germline edits can be passed to future generations.

Germline edits only affect bacteria.

What is a common delivery method in gene therapy?

Viral or non-viral vectors deliver the gene.

Direct protein infusion only.

DNA editing occurs without any carrier.

What does ex vivo gene therapy involve?

Inserting genes directly into the patient’s brain.

Modifying cells outside the body and reinfusing them.

Only editing germ cells.

Which disease areas are targeted by gene therapy?

Neurological disorders, cancer, inherited diseases, infections.

Only metabolic disorders.

Only cosmetic conditions.

What is ProSavin related to?

A gene therapy strategy to restore dopamine in Parkinson’s disease.

A vaccine for malaria.

A CRISPR editing tool.

What is a major ethical concern with germline therapy?

Potential heritable genetic changes across generations.

It only affects plants.

No safety concerns exist.

What role do promoters play in transgenesis?

They control when and where a gene is expressed.

They delete genes.

They encode therapeutic proteins only.

What is a conditional knockout?

A permanent global gene addition.

Gene deletion that occurs in specific tissues or times.

An unrelated protein tagging method.

Which statement is true about gene therapy vectors?

They act as vaccines without delivering genes.

They only edit DNA in test tubes.

They carry the therapeutic gene into target cells.

You can integrate the game into an LMS compatible with LTI 1.1 or LTI 1.3 such as Canvas, Moodle, or Blackboard. This way, the scores will be automatically saved into the platform’s gradebook.

Gene Therapy Primer Quiz

Froggy Jumps

About this activity

Created by

Download the paper version to play

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Gene Therapy Primer QuizOnline version

by Carolina Arias

What is somatic gene therapy?

What distinguishes germline therapy from somatic therapy?

What is a common delivery method in gene therapy?

What does ex vivo gene therapy involve?

Which disease areas are targeted by gene therapy?

What is ProSavin related to?

What is a major ethical concern with germline therapy?

What role do promoters play in transgenesis?

What is a conditional knockout?

Which statement is true about gene therapy vectors?

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