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Pharmacology Chapter 1 Vocabulary
 

Crossword Puzzle

Pharmacology Chapter 1 VocabularyOnline version

Vocabulary for Chapter 1 of the Pharmacology textbook

by Wolf
1

The range of serum concentrations for a particular drug that provides the optimum probability of achieving the desired response with the least probability of toxicity

2

When a drug will cause harm and should NOT be used due to a specific situation such as a disease state, drug interaction, etc

3

A substance that produces an allergic response

4

When one drug increases or prolongs the effect of another drug

5

A fixed quantity of drug being eliminated per unit of time, regardless of concentration of the drug in the body

6

The name under which the manufacturer markets the drug, also known as the "trade name" or "proprietary name"

7

A secondary response to a drug other than the primary therapeutic effect that the drug was intended to produce. Also known as a "side effect"

8

An amount of medication given at regular intervals to keep the drug at the therapeutic level

9

a state in which a person's body adapts physiologically and psychologically to a drug and cannot function without it

10

A branch of pharmacology that studies the drug's molecular, biochemical, and physiologic effects or actions on the body

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Chemical messengers that originate within the body

2

Medical products and practices that are not part of standard care, but are used TOGETHER with conventional practices

3

A method of mathematically describing the process of absorption, distribution, metabolism, and elimination of a drug within the body

4

The quantity of a drug administered at one time

5

A disease, symptom, or condition for which a drug is known to be of benefit

6

The change in the action of a drug that is caused by another drug, food, or substance

7

When a messenger's chemical structure is complementary to the structure of a cell's receptor

8

When a drug completely blocks enzyme activity and impairs the metabolism of another drug, and this cannot be overcome by increasing the dosage of the second drug

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Abbreviation for "complementary and alternative medicine"

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Medicinal products and practices that are not part of standard care

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The identification of a drug without regard to who is manufacturing and marketing the drug. Also known as the "nonproprietary name"

2

An action of a drug that is confined to a specific part of the body

3

Whereby a drug cannot be metabolized by the body

4

What a drug binds to in the body to cause an effect or reaction

5

A constant fraction of the remaining drug being eliminated per unit of time

6

The combined effect of two drugs that is more intense or longer than the sum of their individual effects

7

The study of the activity of a drug within the body over a period of time

8

A fatty molecule that is an important part of the cell membrane

9

A messenger that binds to a particular receptor and inhibits the natural reaction of the body to the messenger

10

A substance that changes the way a living organism functions (also called medicine)

11

An unusual or unexpected response to a drug that is unrelated to the dose given

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The time it takes to eliminate half of the total quantity of drug in the body

2

The glial cells around the central nervous system that presents a barrier to many water-soluble compounds

3

The strength by which a specific messenger binds to its receptor site

4

The combined effect of two drugs

5

An amount of drug that will bring the blood concentration rapidly to a therapeutic dose

6

A system of enzymes that the liver uses to metabolize medications

7

The process of converting drugs to other biochemical compounds and then excreting them through metabolic processing

8

A desired action of a drug in the treatment of a disease or symptom

9

A severe allergic reaction resulting in immediate, life-threatening respiratory distress, usually followed by vascular collapse and shock and accompanied by hives

10

A sequence of chemical steps that convert a drug to a metabolite

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The removal of a drug and its metabolites from the body

3

A decrease in the amount of an enzyme available to metabolize a drug

4

Metabolism in the liver before a drug reaches the systemic circulation

5

A dependence characterized by a perceived need to use a drug to attain psychological and physical effects of mood-altering substances

6

Biologic drugs with a large molecular weight

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A disease, symptom, or condition for which the drug may be beneficial and ALSO may do harm

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A drug produced by rDNA technology

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The body's constant effort to maintain a state of health and stability

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Drug action on a living system

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The study of drugs, including their origins, properties, actions, and effects on the body

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A chemical substance with a low molecular weight

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The use of a drug for purposes other than those prescribed for and/or in amounts that were not directed

4

Red, elevated areas on the body

5

The rate at which a drug is eliminated from a specific volume of blood per unit of time

6

The study of and identification of natural sources for drugs

7

A category of nonprescription drugs that includes vitamins, minerals, and herbs

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The limitation of a drug dosage reached where no greater benefit is seen, or the adverse effects or toxicities of the drug are greater than the benefit

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A generalized, all-inclusive effect on the entire body

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Abnormal accumulation of fluid in tissue

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A molecule that stimulates an immune response

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A type of DNA that has been formed in a laboratory by combining two or more different strands of DNA from different organisms

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Drug used to prevent a disease

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A messenger that binds to a particular receptor and triggers the same cellular response as the body's own chemical messenger

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A branch of pharmacology that studies the drug's molecular, biochemical, and physiologic effects or actions on the body

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The process whereby a drug enters the circulatory system

7

The fraction of the administered dose that is available to the target tissue

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The length of time a drug is at the therapeutic level

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Itchy, raised red or skin colored welts (wheals) that appear on the skin's surface. The condition is also known as "hives".

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The administration of a specific amount, dose number, and dose frequency of a drug

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The magnitude of response of a specific dosage of a drug on the body

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The relationship between the size of a dose and the extent of the response to it

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The converted substance created by metabolizing a drug or biochemical compounds

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A process whereby one drug blocks enzyme activity and impairs the metabolism of another drug, can be overcome by increasing the dosage of the second drug

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The ability of a substance to dissolve in a fluid

5

Uncomfortable and often intense itching

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An acronym standing for "absorption, distribution, metabolism, and elemination"

7

When the amount of drug in a patient's blood gives the desired response

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The process by which a drug moves from the bloodstream into other body fluids and tissues and ultimately to its sites of action

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Drugs used to prevent the occurrence of an infection or a disease

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A local or general reaction of the immune system to a substance

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