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AP propagation

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AP propagation

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AP propagation
 

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AP propagationOnline version

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by Jessica
1

Action potentials are initiated at the ( AIS ) , where there is a high density of - gated channels . Depolarisation of the AIS that reaches triggers these channels to , producing the phase of the action potential .

2

Once initiated , the action potential propagates along the . Depolarisation of one segment triggers the of - gated channels in the next segment , allowing ions to flow and depolarise the membrane . - gated channels slightly later , causing and restoration of the membrane potential locally . The of sodium channels behind the potential ensures propagation .

3

Conduction velocity is affected by axon , with diameters reducing internal resistance , and by the extent of myelination . Finally , periods limit how often action potentials can occur and prevent propagation , with the refractory period preventing any new AP and the refractory period allowing APs only if a stimulus occurs .

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