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Glucose Regulation: Insulin and Glucagon

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Glucose Regulation: Insulin and Glucagon

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Fill in the blanks to recall insulin- and glucagon-mediated glucose regulation.

Created by

Sebnem Mercan
Sebnem Mercan
United States

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Glucose Regulation: Insulin and Glucagon
 

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Glucose Regulation: Insulin and GlucagonOnline version

Fill in the blanks to recall insulin- and glucagon-mediated glucose regulation.

by Sebnem Mercan
1

and glucagon are two hormones that regulate levels . When blood glucose rises after a meal , the releases insulin , which promotes uptake of glucose by muscle and fat cells and stimulates the to store excess glucose as . Conversely , when glucose falls , glucagon is released , signaling the liver to break down glycogen into glucose and release it into the bloodstream . This coordinated action maintains and provides steady energy between meals .

2

In the liver , ________ stimulates ________ to convert into glycogen for storage .

3

Glucagon triggers ________ in the liver , releasing stored into the bloodstream .

4

In the liver , glucose can also be derived from - derived substrates as a step in ________ .

5

The transporter mediates insulin - stimulated glucose entry into ________ and ________ tissues .

6

Glucagon signaling begins at a ________ receptor , activating the protein .

7

Gs activation stimulates to produce ________ as a second messenger .

8

In the liver , ________ activates , altering metabolic pathways to raise blood glucose .

9

PKA activity promotes ________ breakdown while limiting during fasting .

10

Tissues that do NOT respond directly to glucagon include ________ and skeletal .

11

In summary , and coordinate ( liver / adipose / muscle ) metabolism through the - - - axis to regulate , , , and .

 
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