DIURETICS

Froggy Jumps

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Foundation course

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Froggy Jumps DIURETICSOnline version Choose the best answer by Foundation course 1 1. Which diuretic does not inhibit the Na–K–2Cl cotransporter in the thick ascending limb of the loop of Henle? a A. Chlorothiazide b B. Furosemide c C. Ethacrynic acid 2 2. Thiazide diuretics primarily inhibit which transporter? a A. Na–K–2Cl cotransporter b B. Na–Cl cotransporter c C. Na+–H+ exchanger 3 3. Carbonic anhydrase inhibitors increase urinary excretion of which ion directly due to decreased H+ secretion? a A. Calcium b B. Sodium c C. Chloride 4 4. Which agent produces osmotic diuresis? a A. Caffeine b B. Mannitol c C. Spironolactone 5 5. Spironolactone exerts its action primarily by a A. Blocking Na–Cl cotransport b B. Inhibiting carbonic anhydrase c C. Antagonizing aldosterone 6 6. Why do loop diuretics commonly cause hypokalemia? a A. They directly inhibit K+ secretion b B. They increase Na+ delivery to collecting ducts c D. They inhibit aldosterone release 7 7. Carbonic anhydrase inhibitors increase K+ excretion because a A. They directly stimulate K+ channels b B. Decreased H+ secretion facilitates K+ secretion c C. They inhibit ENaC 8 8. Ethanol causes diuresis primarily by a A. Increasing GFR b B. Inhibiting Na+ reabsorption in loop of Henle c C. Inhibiting vasopressin secretion 9 9. Thiazide-induced diuresis is less marked than loop diuretics because they act in the a A. Proximal tubule b B. Thick ascending limb c C. Early distal tubule 10 10.A patient is given mannitol for raised intracranial pressure. The diuresis occurs due to a A. Aldosterone blockade b B. Osmotic retention of water in tubular lumen c C. Inhibition of Na–Cl cotransport 11 11.A drug that blocks ENaC in the collecting duct would most likely a A. Increase K+ excretion b B. Decrease Na+ excretion c C. Decrease K+ excretion 12 12.A patient is given a V2 vasopressin receptor antagonist. The primary site of action a A. Thick ascending limb b B.Early distal tubule c C. Collecting duct

Froggy Jumps

DIURETICSOnline version

Choose the best answer

by Foundation course

1. Which diuretic does not inhibit the Na–K–2Cl cotransporter in the thick ascending limb of the loop of Henle?

A. Chlorothiazide

B. Furosemide

C. Ethacrynic acid

2. Thiazide diuretics primarily inhibit which transporter?

A. Na–K–2Cl cotransporter

B. Na–Cl cotransporter

C. Na+–H+ exchanger

3. Carbonic anhydrase inhibitors increase urinary excretion of which ion directly due to decreased H+ secretion?

A. Calcium

B. Sodium

C. Chloride

4. Which agent produces osmotic diuresis?

A. Caffeine

B. Mannitol

C. Spironolactone

5. Spironolactone exerts its action primarily by

A. Blocking Na–Cl cotransport

B. Inhibiting carbonic anhydrase

C. Antagonizing aldosterone

6. Why do loop diuretics commonly cause hypokalemia?

A. They directly inhibit K+ secretion

B. They increase Na+ delivery to collecting ducts

D. They inhibit aldosterone release

7. Carbonic anhydrase inhibitors increase K+ excretion because

A. They directly stimulate K+ channels

B. Decreased H+ secretion facilitates K+ secretion

C. They inhibit ENaC

8. Ethanol causes diuresis primarily by

A. Increasing GFR

B. Inhibiting Na+ reabsorption in loop of Henle

C. Inhibiting vasopressin secretion

9. Thiazide-induced diuresis is less marked than loop diuretics because they act in the

A. Proximal tubule

B. Thick ascending limb

C. Early distal tubule

10.A patient is given mannitol for raised intracranial pressure. The diuresis occurs due to

A. Aldosterone blockade

B. Osmotic retention of water in tubular lumen

C. Inhibition of Na–Cl cotransport

11.A drug that blocks ENaC in the collecting duct would most likely

A. Increase K+ excretion

B. Decrease Na+ excretion

C. Decrease K+ excretion

12.A patient is given a V2 vasopressin receptor antagonist. The primary site of action

A. Thick ascending limb

B.Early distal tubule

C. Collecting duct

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DIURETICS

Froggy Jumps

About this activity

Created by

Download the paper version to play

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Froggy Jumps

DIURETICSOnline version

by Foundation course

1. Which diuretic does not inhibit the Na–K–2Cl cotransporter in the thick ascending limb of the loop of Henle?

2. Thiazide diuretics primarily inhibit which transporter?

3. Carbonic anhydrase inhibitors increase urinary excretion of which ion directly due to decreased H+ secretion?

4. Which agent produces osmotic diuresis?

5. Spironolactone exerts its action primarily by

6. Why do loop diuretics commonly cause hypokalemia?

7. Carbonic anhydrase inhibitors increase K+ excretion because

8. Ethanol causes diuresis primarily by

9. Thiazide-induced diuresis is less marked than loop diuretics because they act in the

10.A patient is given mannitol for raised intracranial pressure. The diuresis occurs due to

11.A drug that blocks ENaC in the collecting duct would most likely

12.A patient is given a V2 vasopressin receptor antagonist. The primary site of action

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