Cell Cycle & Division Mastery

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Cell cycle control quiz.

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Jaylin Vielka Garcia

United States

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Cell Cycle & Division Mastery


Froggy Jumps Cell Cycle & Division MasteryOnline version Cell cycle control quiz. by Jaylin Vielka Garcia 1 In which phase does DNA replication occur? a G1 phase b M phase c S phase 2 What regulates the cell cycle by activating CDKs? a Phosphatases b Kinases c Cyclins 3 What is the main purpose of mitosis? a Produce two genetically identical daughter cells b Replicate DNA c Graft cells together 4 Which checkpoint prevents progression if DNA is damaged? a G1/S checkpoint b S/M checkpoint c G2/M checkpoint 5 Which protein activates p53 in response to DNA damage? a ATM/ATR kinases b Ras c Ligase 6 What structure forms at the poles during mitosis? a Spindle apparatus b Golgi apparatus c Nucleolus 7 Which phase prepares a cell for mitosis by repairing DNA? a G1 phase b G2 phase c S phase 8 What enzyme unwinds DNA at replication forks? a Helicase b DNA ligase c Topoisomerase 9 Which enzyme seals gaps between Okazaki fragments? a Primase b DNA ligase c Helicase 10 What is the term for programmed cell death? a Autolysis b Necrosis c Apoptosis 11 Which phase follows cytokinesis in the cell cycle? a G1 phase b S phase c M phase 12 Which complex controls progression from G2 to M phase? a Cas9 complex b Cdk–cyclin complex c ATP synthase 13 What is the function of the APC/C complex? a Trigger anaphase and exit mitosis b Replicate DNA c Repair DNA 14 Which structure is responsible for organizing the spindle? a Nucleolus b Centromere c Centrosome 15 What happens during prophase? a Cytokinesis b DNA replication c Chromosomes condense 16 What happens during metaphase? a Cytokinesis begins b Chromosomes align at the metaphase plate c Nuclear envelope reforms 17 What happens during anaphase? a Nuclear envelope forms b Chromosomes condense c Sister chromatids separate 18 What happens during telophase? a Chromosomes attach to spindle b Nuclear envelope re-forms c DNA replication 19 Which phase involves cytokinesis? a S phase b M phase c G1 phase 20 Which checkpoint ensures the genome is undamaged before S phase? a G2/M checkpoint b Spindle assembly checkpoint c G1/S checkpoint 21 Which checkpoint ensures proper chromosome attachment to the spindle? a G1 checkpoint b DNA damage checkpoint c Spindle assembly checkpoint 22 What is the role of p53 in the cell cycle? a Promotes replication b Degrades DNA c DNA damage response and arrest 23 What phase is directly after S phase? a M phase b G2 phase c G1 phase 24 Which molecule pairs with a DNA template during replication? a Ligase b RNA polymerase c DNA polymerase 25 Which structure is key for chromatid cohesion? a Tubulin b Actin c Cohesin 26 What marks the end of mitosis? a Nuclear envelope forms b DNA replication ends c Cytokinesis completes 27 Which phase involves chromatin de-condensation? a Prophase b Telophase c Metaphase 28 What protein forms microtubules of the spindle? a Actin b Tubulin c Keratin 29 Which phase is characterized by chromatid separation? a Anaphase b Metaphase c Prophase 30 What causes cell cycle arrest in many cancers? a p53 pathway dysfunction b Overactive mitochondria c Excess glycolysis 31 Which molecule helps unwind supercoils during replication? a Topoisomerase b Ligase c Primase 32 Which phase builds the mitotic spindle? a Prophase b Anaphase c Telophase 33 What is produced by mitosis to be identical to the parent cell? a Two diploid daughter cells b Two haploid cells c One diploid cell 34 Which regulator closes the G1/S transition if DNA damaged? a Cyclin D b p53 c Ras 35 Which phase involves duplication of centrosomes? a S/G2 interphase b M phase c G1 phase 36 Which organelle helps separate chromosomes during mitosis? a Ribosome b Spindle apparatus c Endoplasmic reticulum 37 Which checkpoint ensures DNA replication is complete? a Spindle checkpoint b G2/M checkpoint c G1/S checkpoint 38 Which phase is characterized by chromosomal condensation? a Prophase b Telophase c Anaphase 39 What triggers cytokinesis in animal cells? a Nuclear envelope breakdown b DNA replication c Contractile ring of actin 40 Which phase duplicates the centromeres? a S phase b M phase c G1 phase 41 What ensures accurate sister chromatid separation? a Securin degradation b Cyclin accumulation c DNA ligation 42 Which molecule marks the metaphase plate alignment? a Actin filaments b Kinetochore microtubules c Intermediate filaments 43 What is the outcome of successful cytokinesis? a DNA repair b Nucleus duplication c Two separate daughter cells 44 Which phase is not part of mitotic division? a Prophase b Metaphase c Interphase 45 Which check ensures DNA integrity before division? a G1 progression checkpoint b DNA damage checkpoint c Spindle checkpoint 46 What does APC/C activation lead to during mitosis? a Nuclear breakdown b Sister chromatid separation c DNA synthesis 47 Which phase involves chromosome decondensation? a Telophase b Prophase c Metaphase 48 Which molecule forms the spindle fiber tracks? a Keratin b Tubulin c Myosin 49 Which protein regulates anaphase onset? a Ligase b DNA polymerase c APC/C complex 50 Which phase is primarily about growth and preparation? a M phase b S phase c G1 phase 51 Which enzyme synthesizes new DNA strands? a Helicase b DNA polymerase c RNA polymerase 52 What ensures sister chromatids stay together until anaphase? a Tubulin complex b Kinase complex c Cohesin complex 53 Which phase features nuclear envelope breakdown? a Telophase b Prometaphase c Metaphase 54 What is the role of cyclin synthesis and degradation? a Time the cell cycle b Synthesize lipids c Repair DNA 55 Which checkpoint ensures proper chromosome-spindle attachment? a G1/S checkpoint b Spindle assembly checkpoint c G2/M checkpoint 56 What triggers cytokinesis in plant cells differently from animals? a Cell plate formation b Contractile ring c Vacuole fusion 57 Which structure disappears during mitosis? a Golgi b Nucleolus c Ribosome 58 What is the consequence of defective p53? a Inhibited replication b Enhanced DNA repair c Uncontrolled cell cycle progression 59 Which phase duplicates the chromosome set? a G1 phase b S phase c M phase 60 Which regulator is a cyclin-dependent kinase partner? a Ligase b Cyclin c Phosphatase 61 Which event marks the end of mitosis? a Nuclear envelope reforms b DNA replication c Chromosome condensation 62 What is the primary function of mitotic spindle? a Secrete enzymes b Separate chromosomes c Synthesize DNA 63 Which phase aligns chromosomes in center of cell? a Prophase b Metaphase c Telophase 64 Which protein forms the contractile ring in cytokinesis? a Actin b Myosin c Tubulin 65 What ensures equal chromosome distribution? a RNA polymerase b DNA ligase c M checkpoint and APC/C 66 Which phase immediately precedes S phase? a G2 phase b G1 phase c M phase 67 Which event occurs during prophase I of meiosis not mitosis? a Chromosome condensation b Spindle formation c Homologous recombination

Cell Cycle & Division Mastery

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Cell Cycle & Division MasteryOnline version

by Jaylin Vielka Garcia

In which phase does DNA replication occur?

What regulates the cell cycle by activating CDKs?

What is the main purpose of mitosis?

Which checkpoint prevents progression if DNA is damaged?

Which protein activates p53 in response to DNA damage?

What structure forms at the poles during mitosis?

Which phase prepares a cell for mitosis by repairing DNA?

What enzyme unwinds DNA at replication forks?

Which enzyme seals gaps between Okazaki fragments?

What is the term for programmed cell death?

Which phase follows cytokinesis in the cell cycle?

Which complex controls progression from G2 to M phase?

What is the function of the APC/C complex?

Which structure is responsible for organizing the spindle?

What happens during prophase?

What happens during metaphase?

What happens during anaphase?

What happens during telophase?

Which phase involves cytokinesis?

Which checkpoint ensures the genome is undamaged before S phase?

Which checkpoint ensures proper chromosome attachment to the spindle?

What is the role of p53 in the cell cycle?

What phase is directly after S phase?

Which molecule pairs with a DNA template during replication?

Which structure is key for chromatid cohesion?

What marks the end of mitosis?

Which phase involves chromatin de-condensation?

What protein forms microtubules of the spindle?

Which phase is characterized by chromatid separation?

What causes cell cycle arrest in many cancers?

Which molecule helps unwind supercoils during replication?

Which phase builds the mitotic spindle?

What is produced by mitosis to be identical to the parent cell?

Which regulator closes the G1/S transition if DNA damaged?

Which phase involves duplication of centrosomes?

Which organelle helps separate chromosomes during mitosis?

Which checkpoint ensures DNA replication is complete?

Which phase is characterized by chromosomal condensation?

What triggers cytokinesis in animal cells?

Which phase duplicates the centromeres?

What ensures accurate sister chromatid separation?

Which molecule marks the metaphase plate alignment?

What is the outcome of successful cytokinesis?

Which phase is not part of mitotic division?

Which check ensures DNA integrity before division?

What does APC/C activation lead to during mitosis?

Which phase involves chromosome decondensation?

Which molecule forms the spindle fiber tracks?

Which protein regulates anaphase onset?

Which phase is primarily about growth and preparation?

Which enzyme synthesizes new DNA strands?

What ensures sister chromatids stay together until anaphase?

Which phase features nuclear envelope breakdown?

What is the role of cyclin synthesis and degradation?

Which checkpoint ensures proper chromosome-spindle attachment?

What triggers cytokinesis in plant cells differently from animals?

Which structure disappears during mitosis?

What is the consequence of defective p53?

Which phase duplicates the chromosome set?

Which regulator is a cyclin-dependent kinase partner?

Which event marks the end of mitosis?